ReviewISRN oncology2014
Primary synovial sarcomas of the mediastinum: a systematic review and pooled analysis of the published literature.
Review in ISRN oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Aggressive primary mediastinal synovial sarcoma resulting in catastrophic airway compromise and fatal hemoptysis.Radiology case reports · 2026Article
- A Case of Primary Synovial Sarcoma of the Posterior Mediastinum: From Diagnostic Challenges to the Surgical Approach.Journal of chest surgery · 2026Article
- Primary thoracic synovial sarcoma in a 45-year-old male: A case report and literature review.Oncology letters · 2026Article
- The Utility of Fine Needle Aspiration (FNA) Biopsy in the Diagnosis of Mediastinal Lesions.Diagnostics (Basel, Switzerland) · 2023Review
- Mediastinal synovial sarcoma invading the right inferior pulmonary vein and left atrium.JTCVS techniques · 2023Article
- Giant middle mediastinal lesions: when tumor size correlates with mesenchymal origin-a retrospective single-center analysis.Mediastinum (Hong Kong, China) · 2023Article
- Spindle cell thymoma and its histological mimickers.Mediastinum (Hong Kong, China) · 2023Review
- A Primary Mediastinal Monophasic Spindle-Cell Synovial Sarcoma with Superior Venacaval Obstruction.Diseases (Basel, Switzerland) · 2022Article
- The value of multidisciplinary team (MDT) management in the diagnosis and treatment of primary intrathoracic synovial sarcomas: a single-center experience.Journal of thoracic disease · 2021Article
- Sarcomas of the mediastinum with epithelioid morphology.Mediastinum (Hong Kong, China) · 2021Review
- Primary mediastinal synovial sarcomas.Mediastinum (Hong Kong, China) · 2020Review
- An overview on the differential diagnostics of tumors of the anterior-superior mediastinum: the pathologist's perspective.Mediastinum (Hong Kong, China) · 2019Review
- [Mesenchymal tumors of the mediastinum].Der Pathologe · 2016Review
- Mesenchymal tumours of the mediastinum--part II.Virchows Archiv : an international journal of pathology · 2015Review
- Imaging features of primary and metastatic extremity synovial sarcoma: a single institute experience of 78 patients.The British journal of radiology · 2015Article
- Pericardial synovial sarcoma: radiological findings.Radiologia brasileiraArticle
- Management of locally advanced primary mediastinal synovial sarcoma.Lung India : official organ of Indian Chest SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. The aim of this systematic review is to attempt to provide a descriptive analysis for cases of synovial sarcoma (SS) arising in the mediastinum and to analyze prognostic factors. Methods. We performed PubMed database search in July 2013. Twenty-two studies, which included 40 patients, form the basis of this review. Demographic and disease-related factors were analyzed for possible influence on survival. Findings were compared with extremity SS studies reported in literature. Results. Sixteen cases (40%) presented with locally advanced unresectable disease, 2 (5%) with metastatic disease, and 22 (55%) with localized resectable disease. Median tumor size was 11 cm (range: 5-20 cm). Thirty patients were assessable for survival and had a 5-year OS of 36%. Completeness of resection was the only factor associated with significant improvement in OS (5-year survival of 63% and 0% in favor of complete resection, P = 0.003). Conclusion. Mediastinal SS is associated with poor prognosis as more cases are diagnosed at an advanced stage and with larger tumor size compared to extremity SS. Complete surgical resection is the only identified factor associated with better prognosis and may result in survival outcomes that are comparable with those for localized SS of the extremity.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.