Evidence map›Paper›PMID 24563677›Full record

ArticleCellular and molecular bioengineering2013

Analysis and Modeling of Chromosome Congression During Mitosis in the Chemotherapy Drug Cisplatin.

Jeremy M Chacón, Melissa K Gardner

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular bioengineering, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jeremy M ChacónGenetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN, USA 55455.
Melissa K GardnerGenetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN, USA 55455.
University of Minnesota · US

Funding

Quantitative Analysis and Modeling of Microtubule Structure and RegulationR01GM103833 · NIGMS · UNIVERSITY OF MINNESOTA · PI GARDNER, MELISSA · 2013 to 2017
$1.4M
Computational Modeling and Analysis of Kinetochore Dynamics during MitosisR21GM100122 · NIGMS · UNIVERSITY OF MINNESOTA · PI GARDNER, MELISSA · 2012 to 2013
$410k
NIGMS NIH HHS R01 GM103833NIGMS NIH HHS R21 GM100122
6 · The paper itself

Abstract

The chemotherapy drug Cisplatin (cis-diamminedichloroplatinum(II)) induces crosslinks within and between DNA strands, and between DNA and nearby proteins. Therefore, Cisplatin-treated cells which progress into cell division may do so with altered chromosome mechanical properties. This could have important consequences for the successful completion of mitosis. Using Total Internal Reflection Fluorescence (TIRF) microscopy of live Cisplatin-treated

Identifiers

PMID24563677
PMCPMC3927914
OpenAlexW1981446838

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.