Evidence map›Paper›PMID 24563502›Full record

ReviewJournal of immunology (Baltimore, Md. : 1950)2014

Standardizing scavenger receptor nomenclature.

Mercy Prabhudas, Dawn Bowdish, Kurt Drickamer, Maria Febbraio, Joachim Herz, Lester Kobzik, Monty Krieger, John Loike, Terry K Means, Soren K Moestrup and 5 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of immunology (Baltimore, Md. : 1950), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 199 citations in OpenAlex.

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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 5 countries.

Mercy PrabhudasDivision of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;
Dawn Bowdish
Kurt Drickamer
Maria Febbraio
Joachim Herz
Lester Kobzik
Monty Krieger
John Loike
Terry K Means
Soren K Moestrup
Steven Post
Tatsuya Sawamura
Samuel Silverstein
Xiang-Yang Wang
Joseph El Khoury
Columbia University · USHarvard University · USAarhus University Hospital · DKImperial College London · GBMassachusetts Institute of Technology · USMcMaster University · CANational Cerebral and Cardiovascular Center · JPNational Institute of Allergy and Infectious Diseases · USSouthwestern Medical Center · USUniversity of Alberta · CAUniversity of Arkansas for Medical Sciences · USVCU Massey Comprehensive Cancer Center

Funding

Generation of a comprehensive panel of reagents for research on scavenger receptoU24AI082660 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI EL-KHOURY, JOSEPH EL, STUART, LYNDA · 2009 to 2013
$4.7M
Metabolism of the VLDL receptor and ApoE receptor 2R37HL063762 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HERZ, JOACHIM J · 2010 to 2019
$4.0M
CD36 in Alzheimer's DiseaseR01NS059005 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI EL-KHOURY, JOSEPH EL · 2008 to 2012
$1.8M
Host-tumor interactions and cancer relapse after radiation therapyR01CA175033 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI WANG, XIANG-YANG SHAWN · 2014 to 2018
$1.6M
Large Stress Proteins in Biology and MedicineR01CA154708 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI WANG, XIANG-YANG SHAWN · 2011 to 2015
$1.5M
Scavenger Receptor-A and Immune RegulationR01CA129111 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI WANG, XIANG-YANG SHAWN · 2007 to 2011
$1.2M
NCI NIH HHS R01 CA129111NCI NIH HHS R01 CA154708NCI NIH HHS R01 CA175033NHLBI NIH HHS R37 HL063762NIAID NIH HHS U24 AI082660NINDS NIH HHS R01 NS059005
6 · The paper itself

Abstract

Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a variety of ligands, including endogenous and modified host-derived molecules and microbial pathogens. There are currently eight classes of scavenger receptors, many of which have multiple names, leading to inconsistencies and confusion in the literature. To address this problem, a workshop was organized by the U.S. National Institute of Allergy and Infectious Diseases, National Institutes of Health to help develop a clear definition of scavenger receptors and a standardized nomenclature based on that definition. Fifteen experts in the scavenger receptor field attended the workshop and, after extensive discussion, reached a consensus regarding the definition of scavenger receptors and a proposed scavenger receptor nomenclature. Scavenger receptors were defined as cell surface receptors that typically bind multiple ligands and promote the removal of non-self or altered-self targets. They often function by mechanisms that include endocytosis, phagocytosis, adhesion, and signaling that ultimately lead to the elimination of degraded or harmful substances. Based on this definition, nomenclature and classification of these receptors into 10 classes were proposed. The discussion and nomenclature recommendations described in this report only refer to mammalian scavenger receptors. The purpose of this article is to describe the proposed mammalian nomenclature and classification developed at the workshop and to solicit additional feedback from the broader research community.

Indexed as

AnimalsHumansReceptors, ScavengerTerminology as TopicReceptors, Scavenger

Identifiers

PMID24563502
PMCPMC4238968
OpenAlexW2172003877

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.