ArticleBiotechnology letters2014
Matrix metalloproteinases are important for follicular development in normal and miniature pigs.
Article in Biotechnology letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Hormonal Signaling and Follicular Regulation in Normal and Miniature Pigs During Corpus Luteum Regression.International journal of molecular sciences · 2025Article
- Design and Application Strategies of Natural Polymer Biomaterials in Artificial Ovaries.Annals of biomedical engineering · 2023Review
- RGD-modified dextran hydrogel promotes follicle growth in three-dimensional ovarian tissue culture in mice.Theriogenology · 2022Article
- Metalloproteases in gonad formation and ovulation.General and comparative endocrinology · 2021Review
- Morphological changes in mouse ovary due to hormonal hypersecretion and matrix metalloproteinase -2 activity.Histology and histopathology · 2021Article
- Regulatory effect of apoptosis on morphological changes in cell mass of porcine blastocyst through supplementation of rapamycin duringJournal of advanced veterinary and animal research · 2020Article
- Matrix metallopeptidases regulate granulosa cell remodeling through the hormone signaling pathway.Journal of advanced veterinary and animal research · 2020Article
- MIR143 Inhibits Steroidogenesis and Induces Apoptosis Repressed by H3K27me3 in Granulosa Cells.Frontiers in cell and developmental biology · 2020Article
- Article
- Gelatin Binding Proteins in Reproductive Physiology.Indian journal of microbiology · 2016Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To determine the differences in the follicular development process of normal and miniature pigs, we compared the expression of matrix metalloproteinases (MMP) in these two breeds throughout folliculogenesis. In normal pigs, MMP-9 was highly expressed in all stages of the follicular development as well as during ovulation. The follicular development exhibited strong gelatinase activity. The expression of MMP-2 remained insignificant throughout folliculogenesis in both breeds. However, for the follicles of miniature pigs, MMP-2 level was higher than that in normal pigs. Thus MMP types may regulate the remodelling of follicular tissue in the ovaries of normal and miniature pigs. The differential expression of MMPs observed in this study reflected the mechanisms underlying ovarian follicular development in these two breeds.
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