ReviewCurrent allergy and asthma reports2014
Recombinant allergens for diagnosis of cockroach allergy.
Review in Current allergy and asthma reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- [Sensitization characteristics of cockroach in Beijing area].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022Article
- IgE reactivity patterns in Asian and central European cockroach-sensitized patients reveal differences in primary sensitizing allergen sources.The journal of allergy and clinical immunology. Global · 2022Article
- Concordance of skin test reactivity between indoor inhalant allergens among children with allergic respiratory disease.BMC pediatrics · 2021Article
- Component-Resolved Diagnosis of American Cockroach (Frontiers in allergy · 2021Article
- IgE and T Cell Reactivity to a Comprehensive Panel of Cockroach Allergens in Relation to Disease.Frontiers in immunology · 2020Article
- Precision medicine allergy immunoassay methods for assessing immunoglobulin E sensitization to aeroallergen molecules.World journal of methodology · 2018Article
- Cross-sectional study on sensitization to mite and cockroach allergen components in allergy patients in the Central European region.Clinical and translational allergy · 2018Article
- N-glycan in cockroach allergen regulates human basophil function.Immunity, inflammation and disease · 2017Article
- New Insights into Cockroach Allergens.Current allergy and asthma reports · 2017Review
- Cross-reaction between Formosan termite (Coptotermes formosanus) proteins and cockroach allergens.PloS one · 2017Article
- Article
- Indoor Allergens and Allergic Respiratory Disease.Current allergy and asthma reports · 2016Review
- Mosquito salivary allergen Aed a 3: cloning, comprehensive molecular analysis, and clinical evaluation.Allergy · 2016Article
- Cockroach allergen exposure and risk of asthma.Allergy · 2016Review
- Antigenic Determinants of the Bilobal Cockroach Allergen Bla g 2.The Journal of biological chemistry · 2016Article
- Different Bla-g T cell antigens dominate responses in asthma versus rhinitis subjects.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2015Article
- Analysis of glutathione S-transferase allergen cross-reactivity in a North American population: Relevance for molecular diagnosis.The Journal of allergy and clinical immunology · 2015Article
- Cockroach allergy and allergen-specific immunotherapy in asthma: potential and pitfalls.Current opinion in allergy and clinical immunology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Molecular cloning of cockroach allergens and their expression as recombinant proteins have allowed a better understanding of the mechanisms of cockroach allergic disease. Recombinant cockroach allergens have been used for skin testing or in vitro methods to measure IgE antibody levels in serum. Early studies evaluating selected U.S. patients revealed that a cocktail of four cockroach allergens, Bla g 1, Bla g 2, Bla g 4, and Bla g 5, would identify 95 % of cockroach allergic patients. More recent studies pointed to an important role of sensitization to tropomyosin among certain populations, and suggested that a cocktail of five allergens Bla g 1 and/or Per a 1, Bla g 2, Bla g 4, Bla g 5, and Bla g 7, and/or Per a 7, would be expected to diagnose 50- 64 % of cockroach-allergic patients worldwide. Variation in IgE reactivity profiles could be in part due to IgE responses to cross-reactive homologous allergens from different origins. The availability of purified natural or recombinant cockroach allergens provides the capacity to improve diagnosis of cockroach allergy and to develop novel forms of immunotherapy for cockroach-allergic patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.