GuidelineIntensive care medicine2014
Clinical practice guideline on diagnosis and treatment of hyponatraemia.
Guideline in Intensive care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 74 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed, 3 syntheses or guidelines pooled it, 1,016 citations in OpenAlex.
- Hyponatremia and aging-related diseases: key player or innocent bystander? A systematic review.Systematic reviews · 2023Pooled it
- Sodium assessment in neonates, infants, and children: a systematic review.European journal of pediatrics · 2022Pooled it
- Guideline
- Secondary Adrenocortical Insufficiency in Liver Cancer Patient After Treatment With Cadonilimab: A Case Report.Clinical medicine insights. Endocrinology and diabetes · 2026Article
- Coexistence of 21-hydroxylase deficiency and Gitelman syndrome in a neonate presenting with severe hyponatremic seizures: a case report.Frontiers in endocrinology · 2026Article
- Development and validation of a nomogram for early nutritional risk stratification in elderly patients with pulmonary sepsis: a retrospective cohort study.Frontiers in nutrition · 2026Article
- Ultrasound evaluation of the optic nerve in patients with severe symptomatic hyponatremia.Internal and emergency medicine · 2025Article
- Hyponatremia in takotsubo syndrome is associated with attenuated in-hospital improvement of left ventricular ejection fraction and higher long-term mortality.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025Article
- Persistent Polyuria in Severe Hyponatremia Secondary to Beer Potomania and Hypokalemia: A Case Report.Cureus · 2025Article
- Effectiveness of Urea and Tolvaptan in the Treatment of Hypotonic Hyponatremia.Journal of clinical medicine · 2025Article
- Cardiomyocyte-specific NHE1 overexpression confers protection against myocardial infarction during hyperglycemia.Cardiovascular diabetology · 2025Article
- Prognosis of Cancer Patients with Severe Hyponatremia in the Emergency Department: A Retrospective Study from the National Cancer Center of China.Current oncology (Toronto, Ont.) · 2025Article
- Comprehensive Analysis of the Correlation Between Immune-Inflammatory Biomarkers and Intestinal Necrosis in Patients With Acute Intestinal Ischemia.Mediators of inflammation · 2025Article
- Case Report: Presumed cerebral salt wasting syndrome in a 10-week-old German Shorthaired Pointer.Frontiers in veterinary science · 2025Article
- Association of baseline serum sodium with long-term outcomes in newly diagnosed coronary heart disease patients without heart failure: a prospective cohort study.Scientific reports · 2024Article
- Article
- Severe hyponatraemia due to high output external biliary drainage corrected with bile refeeding: A case report.SAGE open medical case reports · 2024Article
- Associations between Baseline Hyponatremia and Activities of Daily Living and Muscle Health in Convalescent Stroke Patients.Progress in rehabilitation medicine · 2024Article
- Mechanisms of hyponatremia and diabetes insipidus after acute spinal cord injury: a critical review.Chinese neurosurgical journal · 2023Review
- Observational
14 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issuedHoorn, Ewout [corrected to Hoorn, Ewout J]
Authors and funding
18 authors at 10 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyponatraemia, defined as a serum sodium concentration <135 mmol/L, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. Hyponatraemia is present in 15-20% of emergency admissions to hospital and occurs in up to 20% of critically ill patients. Symptomatology may vary from subtle to severe or even life threatening. Despite this, the management of patients remains problematic. Against this background, the European Society of Intensive Care Medicine, the European Society of Endocrinology and the European Renal Association-European Dialysis and Transplant Association, represented by European Renal Best Practice have developed a Clinical Practice Guideline on the diagnostic approach and treatment of hyponatraemia as a joint venture of three societies representing specialists with a natural interest in hyponatraemia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.