ReviewAge (Dordrecht, Netherlands)2014
Stress, ageing and their influence on functional, cellular and molecular aspects of the immune system.
Review in Age (Dordrecht, Netherlands), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Systematic review of associations between anxiety, depression, and functional/biological aging among cancer survivors.JNCI cancer spectrum · 2024Pooled it
- Is There Association Between Stress and Bruxism? A Systematic Review and Meta-Analysis.Frontiers in neurology · 2020Pooled it
- Work-Related Stress, Physio-Pathological Mechanisms, and the Influence of Environmental Genetic Factors.International journal of environmental research and public health · 2019Pooled it
- Neurobiological and Anti-Inflammatory Effects of a Deep Diaphragmatic Breathing Technique Based on Neofunctional Psychotherapy: A Pilot RCT.Stress and health : journal of the International Society for the Investigation of Stress · 2024Trial
- The enhancing effects of Biobran/MGN-3, an arabinoxylan rice bran, on healthy old adults' health-related quality of life: a randomized, double-blind, placebo-controlled clinical trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Trial
- Effects of 60-day bed rest with and without exercise on cellular and humoral immunological parameters.Cellular & molecular immunology · 2015Trial
- Cellular senescence dysregulates antiviral interferon responses in idiopathic pulmonary fibrosis.bioRxiv : the preprint server for biology · 2026Article
- Biological age and immunosenescence in Colombian centenarians.npj aging · 2026Article
- Determination of post-pandemic impact on activities of daily living and instrumental activities of daily living factors affecting daily living activities of the elderly.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Psychological distress as a putative host-state determinant of cancer immunotherapy response.Frontiers in immunology · 2026Review
- Chronic Stress and Autoimmunity: The Role of HPA Axis and Cortisol Dysregulation.International journal of molecular sciences · 2025Review
- Spaceflight exposome/microgravity effects on the psychoimmunoneuroendocrine system.NPJ microgravity · 2025Review
- Epigenomic profiling of immune cell subtypes reveals H3K27ac-marked stress signatures after long-duration spaceflight.Scientific reports · 2025Article
- Effects of SGLT2 ablation or inhibition on corticosterone secretion in high-fat-fed mice: exploring a nexus with cytokine levels.Diabetologia · 2025Article
- Impact of physical activity on the incidence of psychiatric conditions during childhood: a longitudinal Swedish birth cohort study.British journal of sports medicine · 2025Article
- Supplementation with Bioactive Compounds Improves Health and Rejuvenates Biological Age in Postmenopausal Women.Biomolecules · 2025Article
- The Role of Cortisol and Dehydroepiandrosterone in Obesity, Pain, and Aging.Diseases (Basel, Switzerland) · 2025Review
- Regulation of Stress-Induced Immunosuppression in the Context of Neuroendocrine, Cytokine, and Cellular Processes.Biology · 2025Review
- Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.Cellular & molecular immunology · 2025Article
- The effects of stress on gut virome: Implications on infectious disease and systemic disorders.MicrobiologyOpen · 2024Review
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The immune response is essential for keeping an organism healthy and for defending it from different types of pathogens. It is a complex system that consists of a large number of components performing different functions. The adequate and controlled interaction between these components is necessary for a robust and strong immune response. There are, however, many factors that interfere with the way the immune response functions. Stress and ageing now consistently appear in the literature as factors that act upon the immune system in the way that is often damaging. This review focuses on the role of stress and ageing in altering the robustness of the immune response first separately, and then simultaneously, discussing the effects that emerge from their interplay. The special focus is on the psychological stress and the impact that it has at different levels, from the whole system to the individual molecules, resulting in consequences for physical health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.