ArticleSocial psychiatry and psychiatric epidemiology2014
The prevalence of metabolic syndrome in people with severe mental illness: a mediation analysis.
Article in Social psychiatry and psychiatric epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Antioxidant uric acid in treated and untreated subjects with major depressive disorder: a meta-analysis and meta-regression.European archives of psychiatry and clinical neuroscience · 2018Pooled it
- Obstructive sleep apnea and psychiatric disorders: a systematic review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2015Pooled it
- How to improve the physical health of people with severe mental illness? A multicentric randomized controlled trial on the efficacy of a lifestyle group intervention.European psychiatry : the journal of the Association of European Psychiatrists · 2021Trial
- Effects of Physical Activity on Disordered Eating Behaviours in Individuals With a Psychotic Disorder.Early intervention in psychiatry · 2025Article
- Were anxiety, depression and psychological distress associated with local mortality rates during COVID-19 outbreak in Italy? Findings from the COMET study.Journal of psychiatric research · 2022Article
- Estimation of cardiac QTc intervals in people prescribed antipsychotics: a comparison of correction factors.Therapeutic advances in psychopharmacology · 2022Article
- Accessing acute medical care to protect health: the utility of community treatment orders.General psychiatry · 2022Article
- Twelve-month outcomes in overweight/obese users with mental disorders following a multi-element treatment including diet, physical activity, and positive thinking: The real-world "An Apple a Day" controlled trial.Frontiers in psychiatry · 2022Article
- The Complex Interplay Between Physical Activity and Recovery Styles in Patients With Severe Mental Disorders in a Real-World Multicentric Study.Frontiers in psychiatry · 2022Article
- PTSD and Suicidal Behaviors Amongst L'Aquila 2009 Earthquake Young Survivors.Frontiers in public health · 2021Article
- Pre-Discharge Predictors of 1-Year Rehospitalization in Adolescents and Young Adults with Severe Mental Disorders: A Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2020Article
- Test-retest reliability of the Italian version of the M-BACK questionnaire to assess the barriers, attitudes, confidence, and knowledge of mental health staff regarding metabolic health of psychiatric patients.Brain and behavior · 2020Article
- Elevated Familial Cardiovascular Burden Among Adolescents With Familial Bipolar Disorder.Frontiers in psychiatry · 2019Article
- The utility of outpatient commitment: acute medical care access and protecting health.Social psychiatry and psychiatric epidemiology · 2018Article
- Association of Physical Activity with Alcohol Abuse and Dependence in a Nationally-Representative U.S. Sample.Substance use & misuse · 2017Article
- Nonpsychiatric Outpatient Care for Adults With Serious Mental Illness in California: Who Is Being Left Behind?Psychiatric services (Washington, D.C.) · 2017Article
- Long-Acting Injectable Antipsychotics in Schizophrenia: Literature Review and Practical Perspective, with a Focus on Aripiprazole Once-Monthly.Advances in therapy · 2017Review
- Ethnicity and cardiovascular health inequalities in people with severe mental illnesses: protocol for the E-CHASM study.Social psychiatry and psychiatric epidemiology · 2016Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeople with severe mental illness (SMI) generally have high rates of metabolic syndrome (MetS). Proposed explanations remain conjectural. Relatively little is known about Mets in SMI in Southern Europe, an area with generally healthy dietary traditions. PURPOSE: To establish prevalence rates of MetS in an Italian sample, and testing hypotheses about putative reasons for the excess in the SMI group.
methodsWe compared the prevalence and correlates of MetS in inpatients with SMI and controls randomly chosen from patients undergoing routine maxillofacial surgery. We employed formal tests of mediation.
resultsThe MetS prevalence rate was 26.1 % in the SMI group and 15.9 % in the comparison group. After controlling for age, people with SMI were three times more likely to have MetS than their non-SMI counterparts. Smoking and a family history of cardiovascular disease were strongly related to MetS in both groups. However, these factors could not explain the excess of MetS in the SMI group, and we found no effect of antipsychotic dose.
conclusionsSMI remained prominent in increasing the likelihood of MetS in this low prevalence population, and putative determinants of MetS were common to people with SMI and to controls. Explanations for high MetS rates in SMI may lie in health behaviours other than smoking.
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