ArticleGenetics2014
SNP2GO: functional analysis of genome-wide association studies.
Article in Genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Range-Wide Genomic Analysis of Pygmy Rabbits (Genes · 2026Article
- Linking Personality Traits to Mediterranean Diet Adherence and Exploring Gene-Diet Interactions in Neuroticism.Nutrients · 2025Article
- Widespread temporal niche partitioning in an adaptive radiation of cichlid fishes.Nature ecology & evolution · 2025Article
- Genomic implications of the repeated shift to self-fertilization across a species' geographic distribution.The Journal of heredity · 2025Article
- Association of single nucleotide polymorphisms in Neuropeptide Y (NPY) and Phosphoglycerate Mutase 2 (PGAM2) genes with growth traits in rabbits.Tropical animal health and production · 2024Article
- Intergenomic signatures of coevolution between Tasmanian devils and an infectious cancer.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Common evolutionary trajectory of short life-cycle in Brassicaceae ruderal weeds.Nature communications · 2023Article
- Article
- Sweet Taste Preference: Relationships with Other Tastes, Liking for Sugary Foods and Exploratory Genome-Wide Association Analysis in Subjects with Metabolic Syndrome.Biomedicines · 2021Article
- Influence of environmental conditions at spawning sites and migration routes on adaptive variation and population connectivity in Chinook salmon.Ecology and evolution · 2021Article
- The role of neutral and adaptive genomic variation in population diversification and speciation in two ground squirrel species of conservation concern.Molecular ecology · 2021Article
- Contemporary and historical selection in Tasmanian devils (Proceedings. Biological sciences · 2021Article
- Disease swamps molecular signatures of genetic-environmental associations to abiotic factors in Tasmanian devil (Sarcophilus harrisii) populations.Evolution; international journal of organic evolution · 2020Article
- Evolutionary transcriptomics reveals the origins of olives and the genomic changes associated with their domestication.The Plant journal : for cell and molecular biology · 2019Article
- Genome-wide association analysis for β-hydroxybutyrate concentration in Milk in Holstein dairy cattle.BMC genetics · 2019Article
- Article
- Genome-wide association studies and genomic prediction of breeding values for calving performance and body conformation traits in Holstein cattle.Genetics, selection, evolution : GSE · 2017Article
- Article
- Genetic architecture of nonadditive inheritance in Arabidopsis thaliana hybrids.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Var2GO: a web-based tool for gene variants selection.BMC bioinformatics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genome-wide association studies (GWAS) are designed to identify the portion of single-nucleotide polymorphisms (SNPs) in genome sequences associated with a complex trait. Strategies based on the gene list enrichment concept are currently applied for the functional analysis of GWAS, according to which a significant overrepresentation of candidate genes associated with a biological pathway is used as a proxy to infer overrepresentation of candidate SNPs in the pathway. Here we show that such inference is not always valid and introduce the program SNP2GO, which implements a new method to properly test for the overrepresentation of candidate SNPs in biological pathways.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.