Evidence map›Paper›PMID 24561340›Full record

Trial reportJournal of dentistry2014

Longitudinal monitoring of demineralization peripheral to orthodontic brackets using cross polarization optical coherence tomography.

Alexander Nee, Kenneth Chan, Hobin Kang, Michal Staninec, Cynthia L Darling, Daniel Fried

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of dentistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Application of optical coherence tomography in clinical diagnosis.Journal of X-ray science and technology · 2019
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Active Surveillance of Root Caries in Vivo with CP-OCT.Diagnostics (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Use of Optical Coherence Tomography in Dentistry.International journal of dentistry · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Monitoring silver diamine fluoride application with optical coherence tomography.Proceedings of SPIE--the International Society for Optical Engineering · 2021
    Article
  15. Thermal Imaging of Root Caries In Vivo.Journal of dental research · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexander NeeDepartment of Orofacial Sciences, University of California, San Francisco, San Francisco, CA 94143-0758, United States.
Kenneth ChanDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, San Francisco, CA 94143-0758, United States.
Hobin KangDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, San Francisco, CA 94143-0758, United States.
Michal StaninecDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, San Francisco, CA 94143-0758, United States.
Cynthia L DarlingDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, San Francisco, CA 94143-0758, United States.
Daniel FriedDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, San Francisco, CA 94143-0758, United States. Electronic address: daniel.fried@ucsf.edu.
University of California, San Francisco · US

Funding

Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCTR01DE017869 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FRIED, DANIEL · 2006 to 2014
$2.6M
NIDCR NIH HHS R01 DE017869NIDCR NIH HHS R01-DE17869
6 · The paper itself

Abstract

objectivesThe aim of this study was to test the hypothesis that cross-polarization optical coherence tomography (CP-OCT) can be used to longitudinally monitor demineralization peripheral to orthodontic brackets in an extended clinical study.

methodsA high-speed CP-OCT system was used to acquire 3D volumetric images of the area at the base of orthodontic brackets over a period of 12 months after placement. The reflectivity was measured at 3-month intervals for 12 months to determine if there was increased demineralization. Two teeth were monitored on 20 test subjects and the brackets were bonded using two types of adhesives. This was a randomized controlled clinical study with a split mouth design such that each subject served as his or her own control. On one side, the control premolar was bonded with a bonding agent (Adper Scotchbond from 3M ESPE, St. Paul, MN) and composite (Transbond XT from 3M Unitek, Monrovia, CA) that lacked fluoride. On the other side, the experimental premolar was bonded with a fluoride releasing glass ionomer cement (GC Fuji Ortho LC from GC America, Alsip, IL).

resultsThere was a small but significant increase in the calculated lesion depth and integrated reflectivity over that depth (ΔR) for both adhesive types (p<0.0001) indicating increasing demineralization with time. There was no significant difference in the lesion depth (p=0.22) and ΔR (p=0.91) between the groups with the fluoride releasing glass ionomer cement and the conventional composite.

conclusionsCP-OCT was able to measure a significant increase in demineralization (p<0.0001) at the base of orthodontic brackets over a period of 12 months.

Indexed as

Acrylic ResinsAdolescentAdultAluminum SilicatesBicuspidCariostatic AgentsFemaleFluoridesGlass Ionomer CementsHumansImage Processing, Computer-AssistedImaging, Three-DimensionalLongitudinal StudiesMaleOrthodontic BracketsResin CementsAcrylic ResinsAluminum SilicatesCariostatic AgentsFluoridesFuji Ortho LCGlass Ionomer CementsResin CementsScotchbondTransbond XTCross-polarizationDental cariesFluorideOptical coherence tomography

Identifiers

PMID24561340
PMCPMC4007269
OpenAlexW2011251049

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.