Evidence map›Paper›PMID 24560819›Full record

ReviewExperimental neurology2014

Sex differences in stroke: the contribution of coagulation.

Meaghan Roy-O'Reilly, Louise D McCullough

Abstract readReview
In one paragraph

Review in Experimental neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed.

  1. Article
  2. Article
  3. Molecular heterogeneity in human stroke - What can we learn from the peripheral blood transcriptome?Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  4. Article
  5. Article
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  7. Review
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  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Sex, Endothelial Cell Functions, and Peripheral Artery Disease.International journal of molecular sciences · 2023
    Review
  20. Preconditioning with interleukin-1 alpha is required for the neuroprotective properties of mesenchymal stem cells after ischemic stroke in mice.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Meaghan Roy-O'ReillyUniversity of Connecticut Health Center, School of Medicine, USA.
Louise D McCulloughUniversity of Connecticut Health Center, School of Medicine, USA; The Stroke Center at Hartford Hospital, USA. Electronic address: lmccullough@uchc.edu.

Funding

Gender Differences in Ischemic Cell DeathR01NS055215 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCCULLOUGH, LOUISE D. · 2007 to 2016
$4.3M
NINDS NIH HHS R01 NS055215NINDS NIH HHS R01 R01NS055215
6 · The paper itself

Abstract

Stroke is now the leading cause of adult disability in the United States. Women are disproportionately affected by stroke. Women increasingly outnumber men in the elderly population, the period of highest risk for stroke. However, there is also a growing recognition that fundamental sex differences are present that contribute to differential ischemic sensitivity. In addition, gonadal hormone exposure can impact coagulation and fibrinolysis, key factors in the initiation of thrombosis. In this review we will discuss sex differences in stroke, with a focus on platelets, vascular reactivity and coagulation.

Indexed as

Sex CharacteristicsBlood CoagulationBlood Coagulation FactorsBlood PlateletsCerebrovascular CirculationChromosomes, HumanFemaleHumansMaleStrokeThrombolytic TherapyBlood Coagulation FactorsCerebral ischemiaEstrogenThrombosisVasculatureWomen

Identifiers

PMID24560819
PMCPMC4127336

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.