Evidence map›Paper›PMID 24560724›Full record

ArticleJournal of theoretical biology2014

The split genes of Nanoarchaeum equitans have not originated in its lineage and have been merged in another Nanoarchaeota: a reply to Podar et al.

Massimo Di Giulio

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In one paragraph

Article in Journal of theoretical biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Massimo Di GiulioLaboratory for Molecular Evolution, Institute of Genetics and Biophysics 'Adriano Buzzati Traverso', CNR, Via P. Castellino, 111, 80131 Naples, Italy. Electronic address: massimo.digiulio@ibbr.cnr.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

I reply to the suggestion of Podar et al. (2013) that the split genes of Nanoarchaeun equitans are a derived character, showing that their analysis is mistaken. In particular, I show that the split genes both proteins and tRNAs have not been split in N. equitans and have been on the contrary merged in the nanoarchaeon sequenced recently by Podar et al. (2013). This implies that the main argument of Podar et al. (2013) that there should be: "a unique propensity for splitting in the Nanoarchaeota that is most dramatically manifested in the Nanoarchaeum equitans lineage" is false. On the other hand, the analysis seems to favor the hypothesis that the split genes are an ancestral character. This would strengthen to greater extent a model for the origin of the tRNA molecule.

Indexed as

Genome, ArchaealSymbiosisArchaeal ProteinsNanoarchaeotaSulfolobalesArchaeal ProteinsAncestral charactersEvolutionary stagesParsimonytRNA origin

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.