Evidence map›Paper›PMID 24560271›Full record

ArticleMolecular cell2014

Akt-ivation of RNA splicing.

Gina Lee, John Blenis

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Gene regulation through exon junction complex modularity.Nature structural & molecular biology · 2025
    Review
  3. Review
  4. PTEN arginine methylation by PRMT6 suppresses PI3K-AKT signaling and modulates pre-mRNA splicing.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gina LeeDepartment of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
John BlenisDepartment of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: john_blenis@hms.harvard.edu.
Harvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells must tightly control alternative splicing of RNA to maintain homeostasis; in this issue of Molecular Cell, Sanidas et al. (2014) provide new insights into the regulation of RNA splicing by Akt isoforms through phosphorylation of histone modification machinery.

Indexed as

Alternative SplicingGene Expression Regulation, NeoplasticAnimalsHumansLung NeoplasmsProteinsProto-Oncogene Proteins c-aktRNA-Binding ProteinsTranscription FactorsAKT1 protein, humanAKT3 protein, humanIws1 protein, humanProteinsProto-Oncogene Proteins c-aktRNA-Binding ProteinsTranscription Factors

Identifiers

PMID24560271
OpenAlexW1969445758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.