ArticleActa neuropathologica communications2014
Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer.
Article in Acta neuropathologica communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Comorbid pathologies and their impact on progressive supranuclear palsy: current view.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Severe CTE and TDP-43 pathology in a former professional soccer player with dementia: a clinicopathological case report and review of the literature.Acta neuropathologica communications · 2023Review
- Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts.Acta neuropathologica · 2023Review
- TDP-43 Proteinopathy and Tauopathy: Do They Have Pathomechanistic Links?International journal of molecular sciences · 2022Review
- Applying the Bradford Hill Criteria for Causation to Repetitive Head Impacts and Chronic Traumatic Encephalopathy.Frontiers in neurology · 2022Review
- Chronic Traumatic Encephalopathy and Neuropathological Comorbidities.Seminars in neurology · 2020Review
- The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features.Journal of Alzheimer's disease : JAD · 2018Review
- The Intersection between Ocular and Manual Motor Control: Eye-Hand Coordination in Acquired Brain Injury.Frontiers in neurology · 2017Review
- Characterization of Early Pathological Tau Conformations and Phosphorylation in Chronic Traumatic Encephalopathy.Journal of neuropathology and experimental neurology · 2016Article
- Clinical Approach to Progressive Supranuclear Palsy.Journal of movement disorders · 2016Review
- Alzheimer's disease and chronic traumatic encephalopathy: Distinct but possibly overlapping disease entities.Brain injury · 2016Review
- Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury.Translational psychiatry · 2014Article
- [18F]-T807 tauopathy PET imaging in chronic traumatic encephalopathy.F1000Research · 2014Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
We report the case of a 75-year-old ex-professional boxer who developed diplopia and eye movement abnormalities in his 60's followed by memory impairment, low mood and recurrent falls. Examination shortly before death revealed hypomimia, dysarthria, vertical supranuclear gaze palsy and impaired postural reflexes. Pathological examination demonstrated 4-repeat tau neuronal and glial lesions, including tufted astrocytes, consistent with a diagnosis of progressive supranuclear palsy. In addition, neurofibrillary tangles composed of mixed 3-repeat and 4-repeat tau and astrocytic tangles in a distribution highly suggestive of chronic traumatic encephalopathy were observed together with limbic TDP-43 pathology. Possible mechanisms for the co-occurrence of these two tau pathologies are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.