Evidence map›Paper›PMID 24558636›Full record

ArticleAdvances in bioscience and biotechnology (Print)2013

Role of TGF-

Antonella Chiechi, David L Waning, Keith R Stayrook, Jeroen T Buijs, Theresa A Guise, Khalid S Mohammad

Open access · diamondAbstract read
In one paragraph

Article in Advances in bioscience and biotechnology (Print), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 69 citations in OpenAlex.

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  10. Angiogenic signaling pathways and anti-angiogenic therapy for cancer.Signal transduction and targeted therapy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Antonella ChiechiDivision of Endocrinology, Department of Internal Medicine, Indiana University, Indianapolis, USA.
David L WaningDivision of Endocrinology, Department of Internal Medicine, Indiana University, Indianapolis, USA.
Keith R StayrookDivision of Endocrinology, Department of Internal Medicine, Indiana University, Indianapolis, USA.
Jeroen T BuijsDivision of Endocrinology, Department of Internal Medicine, Indiana University, Indianapolis, USA ; Department of Urology, Medical Center, Leiden University, Leiden, The Netherlands.
Theresa A GuiseDivision of Endocrinology, Department of Internal Medicine, Indiana University, Indianapolis, USA.
Khalid S MohammadDivision of Endocrinology, Department of Internal Medicine, Indiana University, Indianapolis, USA.
Indiana University – Purdue University Indianapolis · US

Funding

Differential TGF-Beta Signaling in Bone Microenviroment: Impact on Tumor GrowthU01CA143057 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI BHOWMICK, NEIL A., GUISE, THERESA A · 2011 to 2015
$2.7M
(PQ9) Novel therapeutic approaches to chemotherapy-induced muscle.R21CA205437 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI WANING, DAVID L · 2016 to 2017
$372k
NCI NIH HHS U01 CA143057
6 · The paper itself

Abstract

Breast cancer is the most prevalent cancer among females worldwide leading to approximately 350,000 deaths each year. It has long been known that cancers preferentially metastasize to particular organs, and bone metastases occur in ~70% of patients with advanced breast cancer. Breast cancer bone metastases are predominantly osteolytic and accompanied by increased fracture risk, pain, nerve compression and hypercalcemia, causing severe morbidity. In the bone matrix, transforming growth factor-

Indexed as

AntibodiesBoneBone MetastasisBone ResorptionBreast CancerSmall Molecule InhibitorsTGF-βTransforming Growth Factor-Beta

Identifiers

PMID24558636
PMCPMC3928102
OpenAlexW2027560347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.