Evidence map›Paper›PMID 24558293›Full record

ArticleLiquid crystals2013

Liquid crystal assemblies in biologically inspired systems.

Cyrus R Safinya, Joanna Deek, Roy Beck, Jayna B Jones, Cecilia Leal, Kai K Ewert, Youli Li

Open access · greenAbstract read
In one paragraph

Article in Liquid crystals, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

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  9. Cationic liposome-nucleic acid complexes for gene delivery and gene silencing.New journal of chemistry = Nouveau journal de chimie · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Cyrus R SafinyaMaterials, Physics, and Molecular, Cellular, & Developmental Biology Departments, University of California, Santa Barbara, CA 93106, USA.
Joanna DeekMaterials, Physics, and Molecular, Cellular, & Developmental Biology Departments, University of California, Santa Barbara, CA 93106, USA ; Chemistry and Biochemistry Department, University of California, Santa Barbara, CA 93106, USA.
Roy BeckMaterials, Physics, and Molecular, Cellular, & Developmental Biology Departments, University of California, Santa Barbara, CA 93106, USA.
Jayna B JonesMaterials, Physics, and Molecular, Cellular, & Developmental Biology Departments, University of California, Santa Barbara, CA 93106, USA.
Cecilia LealMaterials, Physics, and Molecular, Cellular, & Developmental Biology Departments, University of California, Santa Barbara, CA 93106, USA.
Kai K EwertMaterials, Physics, and Molecular, Cellular, & Developmental Biology Departments, University of California, Santa Barbara, CA 93106, USA.
Youli LiMaterials Research Laboratory, University of California, Santa Barbara, CA 93106, USA.
Institut de Biologie Moléculaire et Cellulaire · FRUniversity of California, Santa Barbara · USUniversity of Illinois Urbana-Champaign · US

Funding

Structures of Lipid-DNA Nonviral Gene Delivery Systems 4R01GM059288 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI SAFINYA, CYRUS R · 1999 to 2016
$4.2M
NIGMS NIH HHS R01 GM059288
6 · The paper itself

Abstract

In this paper, which is part of a collection in honor of Noel Clark's remarkable career on liquid crystal and soft matter research, we present examples of biologically inspired systems, which form liquid crystal (LC) phases with their LC nature impacting biological function in cells or being important in biomedical applications. One area focuses on understanding network and bundle formation of cytoskeletal polyampholytes (filamentous-actin, microtubules, and neurofilaments). Here, we describe studies on neurofilaments (NFs), the intermediate filaments of neurons, which form open network nematic liquid crystal hydrogels in axons. Synchrotron small-angle-x-ray scattering studies of NF-protein dilution experiments and NF hydrogels subjected to osmotic stress show that neurofilament networks are stabilized by competing long-range repulsion and attractions mediated by the neurofilament's polyampholytic sidearms. The attractions are present both at very large interfilament spacings, in the

Indexed as

DNAgyroid cubic phaseshexagonal liquid crystalslamellar liquid crystalslipidsnematic hydrogelsNeurofilamentsRNAsmall-angle-x-ray-scattering (SAXS)

Identifiers

PMID24558293
PMCPMC3927920
OpenAlexW2066856492

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.