Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2014
Characteristics of unplanned hospital admissions due to drug-related problems in cancer patients.
Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Identification of Drug Interaction Adverse Events in Patients With COVID-19: A Systematic Review.JAMA network open · 2022Pooled it
- Article
- Impact of the ONCORAL multidisciplinary city-hospital follow-up on older patients with cancer treated with oral anticancer drugs.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Article
- Medication Risks and Their Association with Patient-Reported Outcomes in Inpatients with Cancer.Cancers · 2024Article
- Advances in Transversal Topics Applicable to the Care of Bladder Cancer Patients in the Real-World Setting.Cancers · 2022Review
- Drug-related problems and risk factors related to unplanned hospital readmission among cancer patients in Belgium.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Preventable adverse drug events causing hospitalisation: identifying root causes and developing a surveillance and learning system at an urban community hospital, a cross-sectional observational study.BMJ open quality · 2021Observational
- Drug Related Hospital Admissions; A Systematic Review of the Recent Literatures.Bulletin of emergency and trauma · 2019Review
- Socio-demographic and disease related characteristics associated with unplanned emergency department visits by cancer patients: a retrospective cohort study.BMC health services research · 2019Observational
- Prevalence and risk factors of drug-related hospitalizations in multimorbid patients admitted to an internal medicine ward.PloS one · 2019Observational
- Network analysis of drug-related problems in hospitalized patients with hematologic malignancies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Article
- Impact of a supportive care service for cancer outpatients: management and reduction of hospitalizations. Preliminary results of an integrated model of care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Article
- Prevalence and characteristics of adverse drug reactions at admission to hospital: a prospective observational study.British journal of clinical pharmacology · 2016Observational
- Clinical Relevance of the First Domomedicine Platform Securing Multidrug Chronotherapy Delivery in Metastatic Cancer Patients at Home: The inCASA European Project.Journal of medical Internet research · 2016Article
- Hospital re-admission associated with adverse drug reactions in patients over the age of 65 years.European journal of clinical pharmacology · 2016Article
- Presentation patterns and outcomes of patients with cancer accessing care in emergency departments in Victoria, Australia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016Article
- Oncology nurses awareness of drug interactions.Asia-Pacific journal of oncology nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies have examined drug-related problems (DRPs) that have led to hospital admissions in the general population. However, there is a lack of information on the characteristics of DRPs in the cancer population.
objectiveThe objective of this study was to investigate the type, causality, severity, and preventability of DRPs that result in unplanned hospitalizations among cancer patients.
methodsThis was a prospective, cohort study conducted in two oncology wards between July and December 2012. All patients who were diagnosed with solid tumor or lymphoma and required unplanned hospitalization were included. The incidence of DRPs among hospital admissions was captured, and the nature of the DRPs (causality, severity, and preventability) was characterized.
resultsThere were 1,299 admissions and 1,275 were eligible for analysis. Among the 1,275 eligible admissions, 158 (12.4%) were considered to be associated with a DRP. In the 158 admissions associated with DRPs, 164 DRPs were found. The majority of the DRP-related admissions were adverse drug reactions (ADRs) (n=155/164, 94.5%), probable (n=98, 59.8%), moderately severe (n=155, 94.5%), and probably or definitely preventable (n=86, 52.4%). Most patients with DRPs recovered and were discharged. Febrile neutropenia was the most common adverse drug reaction, and drug combinations involving antihypertensives and long-term corticosteroids raised the risks for potential drug-drug interactions among patients with cancer.
conclusionThe incidence of DRP-induced unplanned hospital admissions was 12.4% among cancer patients. Approximately half of these were preventable events.
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