Wolfram syndrome iPS cells: the first human cell model of endoplasmic reticulum disease.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed.

1. A phase Ib/IIa clinical trial of dantrolene sodium in patients with Wolfram syndrome.JCI insight · 2021
   Trial
2. The double whammy of ER-retention and dominant-negative effects in numerous autosomal dominant diseases: significance in disease mechanisms and therapy.Journal of biomedical science · 2024
   Review
3. Cardiac Wolframinopathies: A Case Report of Myocarditis and a Literature Review of Cardiac Involvement in Wolfram Syndrome 1.Journal of clinical medicine · 2024
   Review
4. Genetic perspectives on childhood monogenic diabetes: Diagnosis, management, and future directions.World journal of diabetes · 2023
   Review
5. There's More Than Meets the Eye: Wolfram Syndrome in a Type I Diabetic Patient.Journal of medical cases · 2023
   Article
6. Paediatric Wolfram syndrome Type 1: should gonadal dysfunction be part of the diagnostic criteria?Frontiers in endocrinology · 2023
   Article
7. Multidimensional analysis and therapeutic development using patient iPSC-derived disease models of Wolfram syndrome.JCI insight · 2022
   Article
8. Wolfram Syndrome: A case report of two sisters Wolfram Syndrome: Case report of two sisters.American journal of ophthalmology case reports · 2022
   Article
9. Wolfram Syndrome 1: From Genetics to Therapy.International journal of environmental research and public health · 2022
   Review
10. Clinical Peculiarities in a Cohort of Patients with Wolfram Syndrome 1.International journal of environmental research and public health · 2022
    Article
11. Human iPSC-derived neurons reveal early developmental alteration of neurite outgrowth in the late-occurring neurodegenerative Wolfram syndrome.American journal of human genetics · 2021
    Article
12. A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome.Laboratory investigation; a journal of technical methods and pathology · 2020
    Article
13. Wolfram syndrome 1 gene regulates pathways maintaining beta-cell health and survival.Laboratory investigation; a journal of technical methods and pathology · 2020
    Article
14. Current Landscape of Treatments for Wolfram Syndrome.Trends in pharmacological sciences · 2019
    Review
15. Monogenic Diabetes in Children and Adolescents: Recognition and Treatment Options.Current diabetes reports · 2018
    Review
16. Genetic and clinical aspects of Wolfram syndrome 1, a severe neurodegenerative disease.Pediatric research · 2018
    Review
17. Wolfram Syndrome: Diagnosis, Management, and Treatment.Current diabetes reports · 2016
    Review
18. A Pair of Siblings With Wolfram Syndrome: A Review of the Literature and Treatment Options.Journal of investigative medicine high impact case reports
    Review
19. When is it MODY? Challenges in the Interpretation of Sequence Variants in MODY Genes.The review of diabetic studies : RDS
    Review

Corrections and comments

• Comment on
  β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.2014

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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