ArticleNature communications2014
A two-locus interaction causes interspecific hybrid weakness in rice.
Article in Nature communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
66 citing papers in PubMed, 116 citations in OpenAlex.
- Harnessing Natural Diversity and Rational Design for Enhanced Plant Immunity.Plant, cell & environment · 2026Review
- Cross incompatibility restricting genome exchange and diversification of primary gene pool in plants: challenges and opportunities.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Review
- An NLR-VOZ seesaw: from asymmetric selection to synthetic broad-spectrum resistance.Stress biology · 2026Article
- Genetic dissection and transcriptomic analysis of a novel high-tillering phenotype in rice derived from weedy rice (Hapcheonaengmi3) and Tongil-type Rice (Milyang23).The plant genome · 2026Article
- Article
- Systematic Analysis of Reproductive Barrier Types and Strengths in Interspecific Hybridization InvolvingPlants (Basel, Switzerland) · 2026Article
- The molecular evolutionary basis of species formation revisited.Trends in genetics : TIG · 2025Review
- Genome-Wide Identification and Functional Prediction of LRR-RLK Family Genes in Foxtail Millet (International journal of molecular sciences · 2025Article
- Genomic structural variation in an alpha/beta hydrolase triggers hybrid necrosis in wheat.Nature communications · 2025Article
- Genome-shock deletion of a hybrid lethality gene breaks a reproductive barrier and facilitates speciation inFrontiers in plant science · 2025Article
- Phenotypic characterization and gene mapping of hybrid necrosis in Triticum durum-Haynaldia villosa amphiploids.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Dysfunction of duplicated pair rice histone acetyltransferases causes segregation distortion and an interspecific reproductive barrier.Nature communications · 2024Article
- Genetic Cause of Hybrid Lethality Observed in Reciprocal Interspecific Crosses betweenInternational journal of molecular sciences · 2024Article
- Mechanisms of Intrinsic Postzygotic Isolation: From Traditional Genic and Chromosomal Views to Genomic and Epigenetic Perspectives.Cold Spring Harbor perspectives in biology · 2023Review
- A recessive LRR-RLK gene causes hybrid breakdown in cotton.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- The COG1-OsSERL2 complex senses cold to trigger signaling network for chilling tolerance in japonica rice.Nature communications · 2023Article
- Unraveling the Diverse Roles of Neglected Genes Containing Domains of Unknown Function (DUFs): Progress and Perspective.International journal of molecular sciences · 2023Review
- Hybrid weakness and continuous flowering caused by compound expression of FTLs inFrontiers in plant science · 2023Article
- Article
- Understanding and overcoming hybrid lethality in seed and seedling stages as barriers to hybridization and gene flow.Frontiers in plant science · 2023Review
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reproductive barriers perform a vital role during speciation. Hybrid weakness, the poorer development of hybrids compared with their parents, hinders gene exchange between different species at the postzygotic stage. Here we show that two incompatible dominant loci (Hwi1 and Hwi2) involving three genes are likely to determine the high temperature-dependent expression of hybrid weakness in interspecific hybrids of rice. Hwi1 comprises two leucine-rich repeat receptor-like kinase (LRR-RLK) genes, 25L1 and 25L2, which are specific to wild rice (Oryza rufipogon) and induce hybrid weakness. Hwi2, a rare allele that is predominantly distributed in indica rice (Oryza sativa), encodes a secreted putative subtilisin-like protease. Functional analysis indicated that pyramiding of Hwi1 and Hwi2 activates the autoimmune response in the basal nodes of hybrids, interrupting root formation and then impairing shoot growth. These findings bring new insights into our understanding of reproductive isolation and may benefit rice breeding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.