ReviewCurrent opinion in immunology2014
Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum.
Review in Current opinion in immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Invariant Natural Killer T Cells in Cancer Immunotherapy: Lipid-Based Modulation, Nanotechnology, and Translational Advances.International journal of molecular sciences · 2026Review
- Development of a novel assay for antigen presentation measurement.Scientific reports · 2025Article
- Loss of Tapasin in Tumors Potentiates T-Cell Recognition and Anti-Tumor Effects of Immune Checkpoint Blockade.Cancer science · 2025Article
- Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self.Cell reports · 2023Article
- Different routes of MHC-I delivery to phagosomes and their consequences to CD8 T cell immunity.Seminars in immunology · 2023Review
- Neoantigens and their potential applications in tumor immunotherapy.Oncology letters · 2022Review
- ERAPs Reduce In Vitro HIV Infection by Activating Innate Immune Response.Journal of immunology (Baltimore, Md. : 1950) · 2021Article
- Vaccination against Nonmutated Neoantigens Induced in Recurrent and Future Tumors.Cancer immunology research · 2020Article
- Tumor-targeted silencing of the peptide transporter TAP induces potent antitumor immunity.Nature communications · 2019Article
- Article
- Dopaminergic neurons show increased low-molecular-mass protein 7 activity induced by 6-hydroxydopamine in vitro and in vivo.Translational neurodegeneration · 2018Article
- Vaccines for established cancer: overcoming the challenges posed by immune evasion.Nature reviews. Cancer · 2016Review
- Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Immunological interactions in radiotherapy-opening a new window of opportunity.Annals of translational medicine · 2016Review
- Endoplasmic reticulum aminopeptidase 1 and rheumatic disease: functional variation.Current opinion in rheumatology · 2015Review
- Immunogenicity of infectious pathogens and vaccine antigens.BMC immunology · 2015Review
- Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen-specific CTL recognition.OncoimmunologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Classical MHC class I molecules open a window into the cell by presenting intracellular peptides (pMHC I) on the surface. The peptides are used for immune surveillance by circulating CD8+ T and NK cells to detect and eliminate infected or tumor cells. Not surprisingly, viruses and tumor cells have evolved immune evasion mechanisms to keep the window shades down and the cytotoxic cells oblivious to their presence. Here, we review counter mechanisms that nevertheless allow the immune system to detect and eliminate cells unable to properly process antigenic peptides in the endoplasmic reticulum.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.