Evidence map›Paper›PMID 24556352›Full record

ArticleJournal of the American Society of Nephrology : JASN2014

Patient-reported and actionable safety events in CKD.

Jennifer S Ginsberg, Min Zhan, Clarissa J Diamantidis, Corinne Woods, Jingjing Chen, Jeffrey C Fink

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Remote Usability Testing and Satisfaction with a Mobile Health Medication Inquiry System in CKD.Clinical journal of the American Society of Nephrology : CJASN · 2015
    Trial
  2. Chronic pain and analgesic use in CKD: implications for patient safety.Clinical journal of the American Society of Nephrology : CJASN · 2015
    Trial
  3. Article
  4. Article
  5. Article
  6. Impact of Adverse Drug Reactions in Patients with End Stage Renal Disease in Greece.International journal of environmental research and public health · 2020
    Article
  7. Article
  8. Review
  9. Key methodological considerations for usability testing of electronic patient-reported outcome (ePRO) systems.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Review
  10. Article
  11. Review
  12. Article
  13. Self-reported Medication Adherence and Adverse Patient Safety Events in CKD.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2015
    Article
  14. Maintaining safety in the dialysis facility.Clinical journal of the American Society of Nephrology : CJASN · 2015
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer S GinsbergDepartment of Medicine and.
Min ZhanDepartment of Epidemiology and Public Health, School of Medicine, and.
Clarissa J DiamantidisDepartment of Medicine and.
Corinne WoodsPharmaceutical Health Services Research, School of Pharmacy, University of Maryland, Baltimore, Maryland.
Jingjing ChenDepartment of Medicine and.
Jeffrey C FinkDepartment of Medicine and Department of Epidemiology and Public Health, School of Medicine, and jfink@medicine.umaryland.edu.

Funding

Does underrecognition of kidney disease affect patient safety?R01DK084017 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI FINK, JEFFREY C · 2010 to 2014
$2.1M
NIDDK NIH HHS R01 DK084017NIDDK NIH HHS R01-DK084017
6 · The paper itself

Abstract

Patients with CKD are at high risk for adverse safety events because of the complexity of their care and impaired renal function. Using data from our observational study of predialysis patients with CKD enrolled in the Safe Kidney Care study, we estimated the baseline frequency of adverse safety events and determined to what extent these events co-occur. We examined patient-reported adverse safety incidents (class I) and actionable safety findings (class II), conditioned on participant use of drugs that might cause such an event, and we used association analysis as a data-mining technique to identify co-occurrences of these events. Of 267 participants, 185 (69.3%) had at least one class I or II event, 102 (38.2%) had more than one event, and 48 (18.0%) had at least one event from both classes. The adjusted conditional rates of class I and class II events ranged from 2.9 to 57.6 per 100 patients and from 2.2 to 8.3 per 100 patients, respectively. The most common conditional class I and II events were patient-reported hypoglycemia and hyperkalemia (serum potassium>5.5 mEq/L), respectively. Reporting of hypoglycemia (in patients with diabetes) and falling or severe dizziness (in patients without diabetes) were most frequently paired with other adverse safety events. We conclude that adverse safety events are common and varied in CKD, with frequent association between disparate events. Further work is needed to define the CKD "safety phenotype" and identify patients at highest risk for adverse safety events.

Indexed as

AgedCross-Sectional StudiesDrug-Related Side Effects and Adverse ReactionsFemaleHumansMaleMiddle AgedRenal Insufficiency, ChronicSelf Reportchronic kidney diseasedata miningpatient safety

Identifiers

PMID24556352
PMCPMC4073439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.