Evidence map›Paper›PMID 24556294›Full record

ReviewInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

Aspirin allergy desensitization in cerebrovascular disease. A report of two cases, literature review and management guide for the neurointerventionalist.

Scott L Zuckerman, David B Seder, Crystiana Tsujiura, Deborah Cushing, Holly Gallup, J Mocco, Richard A Hanel, Robert D Ecker

Abstract readCase ReportsReview
In one paragraph

Review in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Asthma and stroke: a narrative review.Asthma research and practice · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Scott L ZuckermanDepartment of Neurosurgery, Vanderbilt University Medical Center; Nashville, TN, USA - zuckerman.scott@gmail.com.
David B SederDepartment of Neurosurgery, Vanderbilt University Medical Center; Nashville, TN, USA.
Crystiana TsujiuraDepartment of Neurosurgery, Vanderbilt University Medical Center; Nashville, TN, USA.
Deborah CushingDepartment of Neurosurgery, Vanderbilt University Medical Center; Nashville, TN, USA.
Holly GallupDepartment of Neurosurgery, Vanderbilt University Medical Center; Nashville, TN, USA.
J MoccoDepartment of Neurosurgery, Vanderbilt University Medical Center; Nashville, TN, USA.
Richard A HanelDepartment of Neurosurgery, Vanderbilt University Medical Center; Nashville, TN, USA.
Robert D EckerDepartment of Neurosurgery, Vanderbilt University Medical Center; Nashville, TN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspirin (ASA) is the mainstay of treatment in cerebrovascular and systemic vascular disease. ASA hypersensitivity can pose a challenge to achieving optimum medical management prior to and after neurointerventional treatment. Desensitization to ASA is well described in the allergy and cardiovascular literature, but there are no similar discussions specific to neurointervention. The purpose of our study was to describe our experience with ASA hypersensitivity management and review the relevant literature. Two cases of patients with symptomatic cerebrovascular disease requiring neurointervention who were successfully desensitized to their ASA hypersensitivity prior to treatment are described. The subsequent literature is reviewed. Several ASA desensitization protocols exist and have been proven to successfully treat ASA hypersensitivity and allow for ASA therapy to be safely initiated. We describe several previously published protocols. ASA desensitization is a safe and simple way to manage ASA hypersensitivity. We provide comprehensive management guidelines for the neurointerventionalist engaging in ASA desensitization.

Indexed as

AgedAspirinAsthma, Aspirin-InducedCerebrovascular DisordersDesensitization, ImmunologicDose-Response Relationship, DrugHumansMalePlatelet Aggregation InhibitorsTreatment OutcomeAspirinPlatelet Aggregation Inhibitorsallergyaspirindesensitizationintracranial atherosclerosissensitivity

Identifiers

PMID24556294
PMCPMC3971141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.