Evidence map›Paper›PMID 24555784›Full record

ReviewBiology direct2014

A survey of motif finding Web tools for detecting binding site motifs in ChIP-Seq data.

Ngoc Tam L Tran, Chun-Hsi Huang

Abstract readEvaluation StudyReview
In one paragraph

Review in Biology direct, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. HBMC bioinformatics · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Virus evolution · 2021
    Article
  9. Finding de novo methylated DNA motifs.Bioinformatics (Oxford, England) · 2019
    Article
  10. Review
  11. FisherMP: fully parallel algorithm for detecting combinatorial motifs from large ChIP-seq datasets.DNA research : an international journal for rapid publication of reports on genes and genomes · 2019
    Article
  12. Article
  13. Performance evaluation for MOTIFSIM.Biological procedures online · 2018
    Article
  14. Article
  15. Article
  16. MOTIFSIM 2.1: An Enhanced Software Platform for Detecting Similarity in Multiple DNA Motif Data Sets.Journal of computational biology : a journal of computational molecular cell biology · 2017
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ngoc Tam L TranDepartment of Computer Science and Engineering, University of Connecticut, 371 Fairfield Way, Unit 4155, Storrs, CT 06269, USA. ntt10001@engr.uconn.edu.
Chun-Hsi Huang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ChIP-Seq (chromatin immunoprecipitation sequencing) has provided the advantage for finding motifs as ChIP-Seq experiments narrow down the motif finding to binding site locations. Recent motif finding tools facilitate the motif detection by providing user-friendly Web interface. In this work, we reviewed nine motif finding Web tools that are capable for detecting binding site motifs in ChIP-Seq data. We showed each motif finding Web tool has its own advantages for detecting motifs that other tools may not discover. We recommended the users to use multiple motif finding Web tools that implement different algorithms for obtaining significant motifs, overlapping resemble motifs, and non-overlapping motifs. Finally, we provided our suggestions for future development of motif finding Web tool that better assists researchers for finding motifs in ChIP-Seq data.

Indexed as

SoftwareAlgorithmsBinding SitesChromatin ImmunoprecipitationDNAProtein BindingSequence Analysis, ProteinDNA

Identifiers

PMID24555784
PMCPMC4022013

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.