Evidence map›Paper›PMID 24555145›Full record

ArticleISRN obesity2013

Relationship between Birth Weight and Metabolic Status in Obese Adolescents.

David J Hill, Harry Prapavessis, J Kevin Shoemaker, Michelle Jackman, Farid H Mahmud, Cheril Clarson

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ISRN obesity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

David J HillLondon Health Sciences Centre, Lawson Health Research Institute, London, ON, Canada N6A 5W9 ; Lawson Health Research Institute, St Joseph's Health Care, 268 Grosvenor Street, London, ON, Canada N6A 4V2 ; Department of Paediatrics, University of Western Ontario, London, ON, Canada N6A 5A5 ; Department of Medicine, University of Western Ontario, London, ON, Canada N6A 5A5 ; Department of Physiology and Pharmacology, University of Western Ontario, London, ON, Canada N6A 5A5.
Harry PrapavessisSchool of Kinesiology, University of Western Ontario, London, ON, Canada N6A 5A5.
J Kevin ShoemakerSchool of Kinesiology, University of Western Ontario, London, ON, Canada N6A 5A5.
Michelle JackmanLondon Health Sciences Centre, Children's Hospital, London, ON, Canada N6A 5W9 ; Department of Pediatrics , University of Calgary, Calgary, Alberta, Canada.
Farid H MahmudDepartment of Paediatrics, University of Toronto and Hospital for Sick Children, Toronto, ON, Canada M5G 1X8.
Cheril ClarsonLondon Health Sciences Centre, Lawson Health Research Institute, London, ON, Canada N6A 5W9 ; Department of Paediatrics, University of Western Ontario, London, ON, Canada N6A 5A5 ; London Health Sciences Centre, Children's Hospital, London, ON, Canada N6A 5W9.
Western University · CAHospital for Sick Children · CALondon Health Sciences Centre · CAUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective. To examine the relationships between birth weight and body mass index, percent body fat, blood lipids, glycemia, insulin resistance, adipokines, blood pressure, and endothelial function in a cohort of obese adolescents. Design and Methods. Ninety-five subjects aged 10-16 years (mean age 13.5 years) with a body mass index >95th centile (mean [±SEM] 33.0 ± 0.6) were utilized from two prospective studies for obesity prevention prior to any interventions. The mean term birth weight was 3527 ± 64 g (range 1899-4990 g;). Results. Body mass index z-score correlated positively with birth weight (r (2) = 0.05, P = 0.03), but not percent body fat. Insulin resistance negatively correlated with birth weight (r (2) = 0.05, P < 0.001), as did fasting plasma insulin (r (2) = 0.05, P < 0.001); both being significantly greater for subjects of small versus large birth weight (Δ Homeostasis Model Assessment = 2.5 and Δ insulin = 10 pmol/L for birth weight <2.5 kg versus >4.5 kg). Adiponectin, but not leptin, blood pressure z-scores or peripheral arterial tomography values positively correlated with birth weight (r (2) = 0.07, P = 0.008). Conclusions. Excess body mass index in obese adolescents was positively related to birth weight. Birth weight was not associated with cardiovascular risk factors but represented a significant determinant of insulin resistance.

Identifiers

PMID24555145
PMCPMC3901987
OpenAlexW2056325013

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.