Evidence map›Paper›PMID 24555113›Full record

ArticleF1000Research2013

Understanding the association between chromosomally integrated human herpesvirus 6 and HIV disease: a cross-sectional study.

Mundeep K Kainth, Susan G Fisher, Diana Fernandez, Amneris Luque, Caroline B Hall, Anh Thi Hoang, Anisha Lashkari, Alexandra Peck, Lubaba Hasan, Mary T Caserta

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in F1000Research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mundeep K KainthDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
Susan G FisherDepartment of Pharmacy, Temple University School of Medicine, Philadelphia, PA, USA.
Diana FernandezDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, NY, USA.
Amneris LuqueDivision of Infectious Diseases, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA.
Caroline B HallDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
Anh Thi HoangDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
Anisha LashkariDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
Alexandra PeckDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
Lubaba HasanDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
Mary T CasertaDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
University of Rochester Medical Center · US

Funding

Virology/Immunology CoreP30AI078498 · NIAID · UNIVERSITY OF ROCHESTER · PI DEWHURST, STEPHEN · 2008 to 2018
$14.6M
TRAINING IN PEDIATRIC INFECTIOUS DISEASEST32AI007464 · NIAID · UNIVERSITY OF ROCHESTER · PI GIGLIOTTI, FRANCIS · 1995 to 2014
$2.2M
NIAID NIH HHS P30 AI078498NIAID NIH HHS T32 AI007464
6 · The paper itself

Abstract

We conducted a cross-sectional investigation to identify evidence of a potential modifying effect of chromosomally integrated human herpes virus 6 (ciHHV-6) on human immunodeficiency virus (HIV) disease progression and/or severity. ciHHV-6 was identified by detecting HHV-6 DNA in hair follicle specimens of 439 subjects. There was no statistically significant relationship between the presence of ciHHV-6 and HIV disease progression to acquired immunodeficiency syndrome. However, after adjusting for use of antiretroviral therapy, all subjects with ciHHV-6 had low severity HIV disease; these findings were not statistically significant. A multi-center study with a larger sample size will be needed to more precisely determine if there is an association between ciHHV-6 and low HIV disease severity.

Identifiers

PMID24555113
PMCPMC3892924
OpenAlexW4244458927

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.