ArticleLearning & memory (Cold Spring Harbor, N.Y.)2014
Dysgranular retrosplenial cortex lesions in rats disrupt cross-modal object recognition.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Cortical functional connectivity in mouse models of early blindness: enucleation vs. anophthalmia.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Differentiated somatic gene expression is triggered in the dorsal hippocampus and the anterior retrosplenial cortex by hippocampal synaptic plasticity prompted by spatial content learning.Brain structure & function · 2024Article
- Identification of the Neural Correlates Underlying Conflict Resolution Performance Using a Rodent Analogue of the Stroop Tests.Neuroscience · 2023Article
- Time-Varying Functional Connectivity of Rat Brain during Bipedal Walking on Unexpected Terrain.Cyborg and bionic systems (Washington, D.C.) · 2023Article
- Neuronal circuitry for recognition memory of object and place in rodent models.Neuroscience and biobehavioral reviews · 2022Review
- Unique roles for the anterior and posterior retrosplenial cortices in encoding and retrieval of memory for context.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Article
- TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy.Science advances · 2021Article
- Dual-Factor Representation of the Environmental Context in the Retrosplenial Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Time to put the mammillothalamic pathway into context.Neuroscience and biobehavioral reviews · 2021Review
- The retrosplenial cortex and long-term spatial memory: from the cell to the network.Current opinion in behavioral sciences · 2020Review
- Cross-Talk of Low-Level Sensory and High-Level Cognitive Processing: Development, Mechanisms, and Relevance for Cross-Modal Abilities of the Brain.Frontiers in neurorobotics · 2020Review
- Retrosplenial cortex and its role in cue-specific learning and memory.Neuroscience and biobehavioral reviews · 2019Review
- Anterior thalamic nuclei, but not retrosplenial cortex, lesions abolish latent inhibition in rats.Behavioral neuroscience · 2018Article
- When is the rat retrosplenial cortex required for stimulus integration?Behavioral neuroscience · 2018Article
- Spatial Memory Engram in the Mouse Retrosplenial Cortex.Current biology : CB · 2018Article
- A Novel Method for Training Mice in Visuo-Tactile 3-D Object Discrimination and Recognition.Frontiers in behavioral neuroscience · 2018Article
- The rat retrosplenial cortex as a link for frontal functions: A lesion analysis.Behavioural brain research · 2017Article
- The retrosplenial cortex and object recency memory in the rat.The European journal of neuroscience · 2017Article
- Retrosplenial Cortical Contributions to Anterograde and Retrograde Memory in the Monkey.Cerebral cortex (New York, N.Y. : 1991) · 2016Article
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4 authors.
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Abstract
The retrosplenial cortex supports navigation, with one role thought to be the integration of different spatial cue types. This hypothesis was extended by examining the integration of nonspatial cues. Rats with lesions in either the dysgranular subregion of retrosplenial cortex (area 30) or lesions in both the granular and dysgranular subregions (areas 29 and 30) were tested on cross-modal object recognition (Experiment 1). In these tests, rats used different sensory modalities when exploring and subsequently recognizing the same test objects. The objects were first presented either in the dark, i.e., giving tactile and olfactory cues, or in the light behind a clear Perspex barrier, i.e., giving visual cues. Animals were then tested with either constant combinations of sample and test conditions (light to light, dark to dark), or changed "cross-modal" combinations (light to dark, dark to light). In Experiment 2, visual object recognition was tested without Perspex barriers, but using objects that could not be distinguished in the dark. The dysgranular retrosplenial cortex lesions selectively impaired cross-modal recognition when cue conditions switched from dark to light between initial sampling and subsequent object recognition, but no impairment was seen when the cue conditions remained constant, whether dark or light. The combined (areas 29 and 30) lesioned rats also failed the dark to light cross-modal problem but this impairment was less selective. The present findings suggest a role for the dysgranular retrosplenial cortex in mediating the integration of information across multiple cue types, a role that potentially applies to both spatial and nonspatial domains.
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