SynthesisLasers in medical science2015
Efficacy of low-level laser therapy for accelerating tooth movement during orthodontic treatment: a systematic review and meta-analysis.
Synthesis in Lasers in medical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Umbrella review of low-level light therapy: evidence across clinical conditions.Lasers in medical science · 2026Pooled it
- Umbrella review of photobiomodulation/low-level laser therapy and vitamin D in orthodontics: effects on tooth movement, pain, root resorption, and bone biomarkers.BMC oral health · 2026Pooled it
- Effects of photobiomodulation therapy on orthodontically induced inflammatory root resorption: a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Effectiveness of photobiomodulation with low-level lasers on the acceleration of orthodontic tooth movement: an umbrella review.Evidence-based dentistry · 2025Pooled it
- Effectiveness of photobiomodulation with low-level lasers on the acceleration of orthodontic tooth movement: a systematic review and meta-analysis of split-mouth randomised clinical trials.Lasers in medical science · 2023Pooled it
- Effect of the photobiomodulation for acceleration of the orthodontic tooth movement: a systematic review and meta-analysis.Lasers in medical science · 2022Pooled it
- Effect of photobiomodulation therapy on mini-implant stability: a systematic review and meta-analysis.Lasers in medical science · 2021Pooled it
- Effect of diode low-level lasers on fibroblasts derived from human periodontal tissue: a systematic review of in vitro studies.Lasers in medical science · 2016Pooled it
- Efficacy of low-level laser therapy in accelerating tooth movement, preventing relapse and managing acute pain during orthodontic treatment in humans: a systematic review.BMC oral health · 2016Pooled it
- Efficacy of adjunctive laser in non-surgical periodontal treatment: a systematic review and meta-analysis.Lasers in medical science · 2016Pooled it
- Minimally Invasive Techniques to Accelerate the Orthodontic Tooth Movement: A Systematic Review of Animal Studies.BioMed research international · 2015Pooled it
- Effect of low-level laser therapy on en masse retraction in females with bimaxillary dentoalveolar protrusion : A single-center randomized clinical trial.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2025Trial
- Effect of 850 nm LED irradiation on the alignment of crowded mandibular anterior teeth: a randomized controlled clinical trial.Clinical oral investigations · 2024Trial
- The effect of single versus multiple piezocisions on the rate of canine retraction: a randomized controlled trial.BMC oral health · 2024Trial
- Low-level laser therapy, piezocision, or their combination vs. conventional treatment for orthodontic tooth movement : A hierarchical 6-arm split-mouth randomized clinical trial.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2024Trial
- Effect of low-level laser therapy on orthodontic tooth movement during miniscrew-supported maxillary molar distalization in humans: a single-blind, randomized controlled clinical trial.Lasers in medical science · 2023Trial
- Effect of low-level laser therapy on the time needed for leveling and alignment of mandibular anterior crowding.The Angle orthodontist · 2022Trial
- Low-level laser-aided orthodontic treatment of periodontally compromised patients: a randomised controlled trial.Lasers in medical science · 2020Trial
- The effect of low-level laser therapy on tooth movement during canine distalization.Lasers in medical science · 2017Trial
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review aimed to evaluate the efficacy of low-level laser therapy (LLLT) for accelerating tooth movement during orthodontic treatment. An extensive electronic search was conducted by two reviewers. Randomized controlled trials (RCTs) and quasi-RCTs concerning the efficacy of LLLT for accelerating tooth movement during orthodontic treatment were searched in CENTRAL, Medline, PubMed, Embase, China Biology Medicine Disc (CBM), China National Knowledge Infrastructure (CNKI), and Google Scholar. Six RCTs and three quasi-RCTs, involving 211 patients from six countries, were selected from 173 relevant studies. All nine articles were feasible for the systematic review and meta-analysis, five of which were assessed as moderate risk of bias, while the rest were assessed as high risk of bias. The mean difference and the 95 % confidence interval (95 % CI) of accumulative moved distance of teeth were observed among all the researches. The results showed that the LLLT could accelerate orthodontic tooth movement (OTM) in 7 days (mean difference 0.19, 95 % CI [0.02, 0.37], p = 0.03) and 2 months (mean difference 1.08, 95 % CI [0.16, 2.01], p = 0.02). Moreover, a relatively lower energy density (5 and 8 J/cm(2)) was seemingly more effective than 20 and 25 J/cm(2) and even higher ones.
Indexed as
Identifiers
24554452What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.