ReviewDrugs2014
Drug treatment of hypertension in pregnancy.
Review in Drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 130 citations in OpenAlex.
- Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review.European journal of clinical pharmacology · 2022Pooled it
- Adverse pregnancy outcomes associated with first-trimester exposure to angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers: A systematic review and meta-analysis.Pharmacology research & perspectives · 2020Pooled it
- Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.British journal of clinical pharmacology · 2018Pooled it
- Impact of a case management model on maternal and neonatal outcomes in gestational hypertension: a randomized controlled trial.Frontiers in global women's health · 2026Article
- ISUOG Consensus Statement on maternal hemodynamic assessment in hypertensive disorders of pregnancy and fetal growth restriction.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025Article
- Effectiveness of antihypertensive therapies and maternal-neonatal outcomes in preeclampsia and eclampsia women: an analytical retrospective study from sudan.Journal of family medicine and primary care · 2025Article
- AttBiomarker: unveiling preeclampsia biomarkers and molecular pathways through two-stage gene selection techniques and attention-based CNN with gene regulatory network analysis.Briefings in bioinformatics · 2025Article
- A Review of Dietary and Lifestyle Management of Pre-Eclampsia and Postpartum Eclampsia.Preventive nutrition and food science · 2025Review
- Plasma from hypertensive pregnancy patients induce endothelial dysfunction even under atheroprotective shear stress.Scientific reports · 2025Article
- Hypertensive disorders of pregnancy: advances in understanding and management.Clinical hypertension · 2025Review
- Outpatient management of essential hypertension: a review based on the latest clinical guidelines.Annals of medicine · 2024Review
- Biomarkers and point of care screening approaches for the management of preeclampsia.Communications medicine · 2024Review
- Diagnosis and Treatment of Eclampsia.Journal of cardiovascular development and disease · 2024Review
- The Nitrate-Nitrite-Nitric Oxide Pathway: Potential Role in Mitigating Oxidative Stress in Hypertensive Disorders of Pregnancy.Nutrients · 2024Review
- Antihypertensive Medication Use before and during Pregnancy and the Risk of Severe Maternal Morbidity in Individuals with Prepregnancy Hypertension.American journal of perinatology · 2024Article
- Preeclampsia, antihypertensive medication use in pregnancy and risk of childhood cancer in offspring.Cancer causes & control : CCC · 2024Article
- The Management of Preeclampsia: A Comprehensive Review of Current Practices and Future Directions.Cureus · 2024Review
- 2023 Korean Endocrine Society Consensus Guidelines for the Diagnosis and Management of Primary Aldosteronism.Endocrinology and metabolism (Seoul, Korea) · 2023Article
- Catestatin-A Potential New Therapeutic Target for Women with Preeclampsia? An Analysis of Maternal Serum Catestatin Levels in Preeclamptic Pregnancies.Journal of clinical medicine · 2023Article
- Eclampsia: A Critical Pregnancy Complication Demanding Enhanced Maternal Care: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Hypertensive disorders represent major causes of pregnancy-related maternal mortality worldwide. Similar to the non-pregnant population, hypertension is the most common medical disorder encountered during pregnancy and is estimated to occur in about 6-8 % of pregnancies. A recent report highlighted hypertensive disorders as one of the major causes of pregnancy-related maternal deaths in the USA, accounting for 579 (12.3 %) of the 4,693 maternal deaths that occurred between 1998 and 2005. In low-income and middle-income countries, preeclampsia and its convulsive form, eclampsia, are associated with 10-15 % of direct maternal deaths. The optimal timing and choice of therapy for hypertensive pregnancy disorders involves carefully weighing the risk-versus-benefit ratio for each individual patient, with an overall goal of improving maternal and fetal outcomes. In this review, we have compared and contrasted the recommendations from different treatment guidelines and outlined some newer perspectives on management. We aim to provide a clinically oriented guide to the drug treatment of hypertension in pregnancy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.