Evidence map›Paper›PMID 24554057›Full record

ArticleCellular and molecular life sciences : CMLS2014

Gene-ethanol interactions underlying fetal alcohol spectrum disorders.

Neil McCarthy, Johann K Eberhart

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  3. The Role of the Hedgehog Pathway in Alcohol-Induced Birth Defects.Advances in experimental medicine and biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Neil McCarthyMolecular Biosciences, Waggoner Center for Alcohol and Addiction Research, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, 78713, USA.
Johann K Eberhart
The University of Texas at Austin · US

Funding

Genetic Screens in Zebrafish to Identify Gene-Ethanol InteractionsR01AA023426 · NIAAA · UNIVERSITY OF TEXAS AT AUSTIN · PI JOHANN K EBERHART · 2015 to 2026
$3.0M
Genetic Hierarchies and Cellular Behaviors during Zebrafish PalatogenesisR00DE018088 · NIDCR · UNIVERSITY OF TEXAS AT AUSTIN · PI EBERHART, JOHANN K · 2008 to 2010
$771k
NIAAA NIH HHS R01 AA023426NIDCR NIH HHS R00 DE018088
6 · The paper itself

Abstract

Fetal alcohol spectrum disorders (FASD) is an umbrella term that describes a diverse set of ethanol-induced defects. The phenotypic variation is generated by numerous factors, including timing and dosage of ethanol exposure as well as genetic background. We are beginning to learn about how the concentration, duration, and timing of ethanol exposure mediate variability within ethanol teratogenesis. However, little is known about the genetic susceptibilities in FASD. Studies of FASD animal models are beginning to implicate a number of susceptibility genes that are involved in various pathways. Here we review the current literature that focuses on the genetic predispositions in FASD.

Indexed as

Gene-Environment InteractionEthanolFemaleFetal Alcohol Spectrum DisordersHedgehog ProteinsHumansIntercellular Signaling Peptides and ProteinsMaternal ExposureMetabolic Networks and PathwaysModels, GeneticPhenotypeEthanolHedgehog ProteinsIntercellular Signaling Peptides and Proteins

Identifiers

PMID24554057
PMCPMC11114006
OpenAlexW2057293916

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.