ArticleFunctional & integrative genomics2014
Heavy metals induce oxidative stress and genome-wide modulation in transcriptome of rice root.
Article in Functional & integrative genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 113 citations in OpenAlex.
- Plant Responses to Heavy Metal Stress: Molecular Mechanisms, Transcriptomic Regulation, and Multi-Omics Integration in Crop Improvement.Plants (Basel, Switzerland) · 2026Review
- Gas chromatography-time-of-flight mass spectrometry (GC-TOFMS)-based metabonomic response ofPeerJ · 2026Article
- Omics advancements towards exploring arsenic toxicity and tolerance in plants: a review.Planta · 2025Review
- Abiotic Stress in Rice: Visiting the Physiological Response and Its Tolerance Mechanisms.Plants (Basel, Switzerland) · 2023Review
- How heavy metal stress affects the growth and development of pulse crops: insights into germination and physiological processes.3 Biotech · 2023Review
- Phosphorus Regulates the Level of Signaling Molecules in Rice to Reduce Cadmium Toxicity.Current issues in molecular biology · 2022Article
- Indole pyruvate decarboxylase gene regulates the auxin synthesis pathway in rice by interacting with the indole-3-acetic acid-amido synthetase gene, promoting root hair development under cadmium stress.Frontiers in plant science · 2022Article
- Hairy roots: An untapped potential for production of plant products.Frontiers in plant science · 2022Review
- Melatonin Modulates Plant Tolerance to Heavy Metal Stress: Morphological Responses to Molecular Mechanisms.International journal of molecular sciences · 2021Review
- Metal and Metalloid Toxicity in Plants: An Overview on Molecular Aspects.Plants (Basel, Switzerland) · 2021Review
- Heavy-Metal Phytoremediation from Livestock Wastewater and Exploitation of Exhausted Biomass.International journal of environmental research and public health · 2021Review
- Molecular Interaction and Evolution of Jasmonate Signaling With Transport and Detoxification of Heavy Metals and Metalloids in Plants.Frontiers in plant science · 2021Review
- Glycine Betaine Accumulation, Significance and Interests for Heavy Metal Tolerance in Plants.Plants (Basel, Switzerland) · 2020Review
- Heavy Metal Stress-Associated Proteins in Rice andFrontiers in genetics · 2020Article
- Genome-wide identification and expression analysis of Hsp70, Hsp90, and Hsp100 heat shock protein genes in barley under stress conditions and reproductive development.Functional & integrative genomics · 2019Article
- Safe Cultivation ofMicroorganisms · 2019Article
- Article
- Long- and short-term protective responses of rice seedling to combat Cr(VI) toxicity.Environmental science and pollution research international · 2018Article
- Toxicological evaluation of therapeutic and supra-therapeutic doses of Cellgevity® on reproductive function and biochemical indices in Wistar rats.BMC pharmacology & toxicology · 2018Article
- Arsenic-silicon priming of rice (Oryza sativa L.) seeds influence mineral nutrient uptake and biochemical responses through modulation of Lsi-1, Lsi-2, Lsi-6 and nutrient transporter genes.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Industrial growth, ecological disturbances and agricultural practices have contaminated the soil and water with many harmful compounds, including heavy metals. These heavy metals affect growth and development of plants as well as cause severe human health hazards through food chain contamination. In past, studies have been made to identify biochemical and molecular networks associated with heavy metal toxicity and uptake in plants. Studies suggested that most of the physiological and molecular processes affected by different heavy metals are similar to those affected by other abiotic stresses. To identify common and unique responses by different metals, we have studied biochemical and genome-wide modulation in transcriptome of rice (IR-64 cultivar) root after exposure to cadmium (Cd), arsenate [As(V)], lead (Pb) and chromium [Cr(VI)] in hydroponic condition. We observed that root tissue shows variable responses for antioxidant enzyme system for different heavy metals. Genome-wide expression analysis suggests variable number of genes differentially expressed in root in response to As(V), Cd, Pb and Cr(VI) stresses. In addition to unique genes, each heavy metal modulated expression of a large number of common genes. Study also identified cis-acting regions of the promoters which can be determinants for the modulated expression of the genes in response to different heavy metals. Our study advances understanding related to various processes and networks which might be responsible for heavy metal stresses, accumulation and detoxification.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.