Trial reportPsychopharmacology2014
Relationships between impulsivity and subjective response in an IV ethanol paradigm.
Trial report in Psychopharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 32 citations in OpenAlex.
- Subjective response to alcohol in young adults with bipolar disorder and recent alcohol use: a within-subject randomized placebo-controlled alcohol administration study.Psychopharmacology · 2023Trial
- Differential effects of UPPS-P impulsivity on subjective alcohol response and craving: An experimental test of acquired preparedness.Experimental and clinical psychopharmacology · 2023Trial
- Neural correlates of inhibitory control are associated with stimulant-like effects of alcohol.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Trial
- Poor inhibitory control is associated with greater stimulation and less sedation following alcohol.Psychopharmacology · 2020Trial
- Relationships between generalized impulsivity and subjective stimulant and sedative responses following alcohol administration.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019Trial
- Associations Between Behavioral and Neural Correlates of Inhibitory Control and Amphetamine Reward Sensitivity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Trial
- Trial
- Testing neurobiological models of reward/incentive sensitization in the continuation of alcohol use disorder (AUD) symptoms in young adults with AUD: A four-year longitudinal study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Interplay of cultural beliefs, psychological disposition, and social milieu during childhood on development of substance use disorder by early adulthood.Experimental and clinical psychopharmacology · 2025Article
- A pilot study of impulsivity and subjective alcohol response in the lab and moment.Experimental and clinical psychopharmacology · 2025Article
- Nucleus accumbens functional connectivity changes underlying alcohol expectancies in bipolar disorder and prospective alcohol outcomes: a within-subject randomized placebo-controlled alcohol administration fMRI study.Frontiers in neuroscience · 2025Article
- Genetic influences on alcohol sensitivity: A critical review.Current addiction reports · 2024Article
- The Relationship Between Men's Sociosexuality, Drinking Intake, and Blackouts.Substance use & misuse · 2024Article
- Planned versus unplanned drinking and cannabis use: Do facets of trait impulsivity influence daily risk?Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023Article
- Moderators of subjective response to alcohol in the human laboratory.Alcoholism, clinical and experimental research · 2022Article
- Impulsivity and the effects of alcohol in women with a history of childhood sexual abuse: A pilot study.Experimental and clinical psychopharmacology · 2021Article
- Rewarding Subjective Effects of the NMDAR Antagonist Nitrous Oxide (Laughing Gas) Are Moderated by Impulsivity and Depressive Symptoms in Healthy Volunteers.The international journal of neuropsychopharmacology · 2021Article
- Subjective response to alcohol: Associated alcohol use and orbitofrontal gray matter volume in bipolar disorder.Journal of affective disorders · 2021Article
- To Infuse or Ingest in Human Laboratory Alcohol Research.Alcoholism, clinical and experimental research · 2020Review
- An Evaluation of Alcohol Sensitivity in the Context of the Acquired Preparedness Model.Addiction research & theory · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
rationaleImpulsivity and individual differences in subjective response to alcohol are risk factors for alcohol problems and possibly endophenotypes for alcohol dependence. Few prior studies have addressed relationships between the two constructs.
objectivesTo predict subjective responses to ethanol, we tested self-reported impulsiveness, ethanol dose condition (high dose, low dose, or placebo), and time (seven time points) along with interactions among these variables.
methodsThe present study is a secondary analysis of data from a within-subject, placebo-controlled, dose-ranging ethanol administration study using IV infusion with a clamping technique to maintain steady-state breath alcohol concentration. The sample consisted of healthy, non-alcohol dependent social alcohol drinkers between the ages of 21 and 30 (N=105). Participants at varying levels of impulsivity were compared with regard to stimulant and subjective responses to three ethanol dose conditions over time.
resultsIndividuals with higher impulsivity reported elavated stimulant and dampened sedative response to alcohol, particularly at the higher dose. Higher impulsivity was associated with a steeper increase in stimulant effects during the first half of clamped ethanol infusion with the higher dose.
conclusionsThese results suggest that impulsive individuals may experience enhanced reinforcing, stimulant effects, and relatively muted aversive sedative effects from alcohol. These subjective responses may relate to enhanced risk of alcohol problems among more impulsive individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.