Evidence map›Paper›PMID 24553200›Full record

ArticleMMWR. Morbidity and mortality weekly report2014

Follow-up of infants diagnosed with HIV - Early Infant Diagnosis Program, Francistown, Botswana, 2005-2012.

Catherine Motswere-Chirwa, Andrew Voetsch, Lydia Lu, Victor Letsholathebe, Phenyo Lekone, Esther Machakaire, Keitumetse Legwaila, Stembile Matambo, Maruping Maruping, Thatayotlhe Kolobe and 8 more

Open access · greenAbstract read
In one paragraph

Article in MMWR. Morbidity and mortality weekly report, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Diagnosis of Human Immunodeficiency Virus Infection.Clinical microbiology reviews · 2019
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Survival of HIV-1 vertically infected children.Current opinion in HIV and AIDS · 2016
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Brief Report: Impact of Option B+ on the Infant PMTCT Cascade in Lilongwe, Malawi.Journal of acquired immune deficiency syndromes (1999) · 2015
    Observational
  17. Article
  18. Getting to 90-90-90 in paediatric HIV: What is needed?Journal of the International AIDS Society · 2015
    Article
  19. 90-90-90--Charting a steady course to end the paediatric HIV epidemic.Journal of the International AIDS Society · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Catherine Motswere-Chirwa
Andrew Voetsch
Lydia Lu
Victor Letsholathebe
Phenyo Lekone
Esther Machakaire
Keitumetse Legwaila
Stembile Matambo
Maruping Maruping
Thatayotlhe Kolobe
Chipo Petlo
Refeletswe Lebelonyane
Mary Glenshaw
Helen Dale
Margarett Davis
Shenaaz El Halabi
Andrew Pelletier
Centers for Disease Control and Prevention (CDC)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2011 prevalence of human immunodeficiency virus (HIV) among pregnant women in Botswana was 30.4%. High coverage rates of HIV testing and antiretroviral prophylaxis have reduced the rate of mother-to-child transmission of HIV in Botswana from as high as 40% with no prophylaxis to <4% in 2011. In June 2005, the national Early Infant Diagnosis (EID) Program began testing HIV-exposed infants (i.e., those born to HIV-infected mothers) for HIV using polymerase chain reaction (PCR) at 6 weeks postpartum. During 2005-2012, follow-up of all HIV-infected infants diagnosed in all 13 postnatal care facilities in Francistown, Botswana, was conducted to ascertain patient outcomes. A total of 202 infants were diagnosed with HIV. As of September 2013, 82 (41%) children were alive and on antiretroviral therapy (ART), 79 (39%) had died, and 41 (20%) were either lost to follow-up, had transferred, or their mothers declined ART. Despite success in preventing mother-to-child transmission in Botswana, results of the EID program highlight the need for early diagnosis of HIV-infected infants, prompt initiation of ART, and retention in care.

Indexed as

Anti-HIV AgentsBotswanaCounselingFemaleFollow-Up StudiesHIV InfectionsHumansInfantInfectious Disease Transmission, VerticalMalePolymerase Chain ReactionPregnancyPregnancy Complications, InfectiousProgram EvaluationSurvival RateTreatment OutcomeAnti-HIV Agents

Identifiers

PMID24553200
PMCPMC4584761
OpenAlexW1931103461

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.