Evidence map›Paper›PMID 24552873›Full record

ArticleParkinsonism & related disorders2014

Mosaicism of alpha-synuclein gene rearrangements: report of two unrelated cases of early-onset parkinsonism.

C Perandones, J C Giugni, D S Calvo, G B Raina, L De Jorge Lopez, V Volpini, C P Zabetian, I F Mata, M Caputo, D Corach and 2 more

Open access · bronzeAbstract readCase ReportsLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Parkinsonism & related disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. α-Synuclein and Parkinsonism: Updates and Future Perspectives.Current neurology and neuroscience reports · 2017
    Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

C PerandonesParkinson's Disease and Movement Disorders Program, Hospital de Clínicas, University of Buenos Aires, Ciudad Autonoma de Buenos Aires C1120AAR, Argentina; National Agency of Laboratories and Health Institutes of Argentina (ANLIS) Dr. Carlos G. Malbrán, Buenos Aires, Argentina. Electronic address: claudia.perandones@gmail.com.
J C GiugniParkinson's Disease and Movement Disorders Program, Hospital de Clínicas, University of Buenos Aires, Ciudad Autonoma de Buenos Aires C1120AAR, Argentina.
D S CalvoParkinson's Disease and Movement Disorders Program, Hospital de Clínicas, University of Buenos Aires, Ciudad Autonoma de Buenos Aires C1120AAR, Argentina.
G B RainaParkinson's Disease and Movement Disorders Program, Hospital de Clínicas, University of Buenos Aires, Ciudad Autonoma de Buenos Aires C1120AAR, Argentina.
L De Jorge LopezInstitut d'Investigació Biomédica de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain.
V VolpiniInstitut d'Investigació Biomédica de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain.
C P ZabetianUniversity of Washington and VA Puget Sound Health Care System, Seattle, WA, United States.
I F MataUniversity of Washington and VA Puget Sound Health Care System, Seattle, WA, United States.
M CaputoServicio de Huellas Digitales Genéticas, School of Pharmacy and Biochemistry, University of Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina.
D CorachServicio de Huellas Digitales Genéticas, School of Pharmacy and Biochemistry, University of Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina.
M RadrizzaniNational University of San Martin, Laboratory of Neuro and Molecular Cytogenetic (CONICET), Buenos Aires, Argentina.
F E MicheliParkinson's Disease and Movement Disorders Program, Hospital de Clínicas, University of Buenos Aires, Ciudad Autonoma de Buenos Aires C1120AAR, Argentina.
Universidad de Buenos Aires · ARInstitut d'Investigació Biomédica de Bellvitge · ESUniversity of Washington · USConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

Using Multiplex Families to map Genes that Modify Susceptibility and Age at OnsetR01NS065070 · NINDS · UNIVERSITY OF WASHINGTON · PI ZABETIAN, CYRUS P · 2009 to 2012
$2.0M
NINDS NIH HHS R01 NS065070
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MosaicismAdultalpha-SynucleinGene RearrangementHumansMaleParkinsonian DisordersYoung Adultalpha-SynucleinGene multiplicationMosaicismParkinson's diseaseα-Synuclein

Identifiers

PMID24552873
PMCPMC4197942
OpenAlexW2167354379

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.