Evidence map›Paper›PMID 24552832›Full record

SynthesisCirculation2014

Effect of childhood obesity prevention programs on blood pressure: a systematic review and meta-analysis.

Li Cai, Yang Wu, Renee F Wilson, Jodi B Segal, Miyong T Kim, Youfa Wang

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Circulation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 135 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. What childhood obesity prevention programmes work? A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2015
    Pooled it
  4. Trial
  5. Review
  6. Tackling the epidemic of obesity and hypertension in children and young people.Current opinion in nephrology and hypertension · 2026
    Review
  7. Article
  8. Tracking of blood pressure levels from childhood.Pediatric nephrology (Berlin, Germany) · 2025
    Review
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  10. Review
  11. Article
  12. Article
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  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Li CaiJohns Hopkins Global Center on Childhood Obesity, Department of International Health, Bloomberg School of Public Health, Baltimore, MD (L.C., Y. Wu, Y. Wang); Department of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing, China (L.C.); Departments of Health, Behavior, and Society (Y. Wu) and Health Policy and Management (R.F.W., J.B.S.), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (J.B.S.); School of Nursing, University of Texas at Austin (M.T.K.); and Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, State University of New York (Y. Wang).
Yang Wu
Renee F Wilson
Jodi B Segal
Miyong T Kim
Youfa Wang
Johns Hopkins Medicine · USJohns Hopkins University · USPeking University · CNThe University of Texas at Austin · US

Funding

MULTILEVEL SYSTEMS-ORIENTED CHILDHOOD OBESITY STUDY IN CHINAU54HD070725 · NICHD · JOHNS HOPKINS UNIVERSITY · PI GITTELSOHN, JOEL · 2011 to 2016
$15.9M
Causes and Interventions for Childhood Obesity:Innovative Systems AnalysisR01HD064685 · NICHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WANG, YOUFA · 2010 to 2013
$1.2M
NICHD NIH HHS 1R01HD064685-01A1NICHD NIH HHS R01 HD064685NICHD NIH HHS U54 HD070725NICHD NIH HHS U54HD070725
6 · The paper itself

Abstract

backgroundChildhood overweight and obesity are associated with elevated blood pressure (BP). However, little is known about how childhood obesity lifestyle prevention programs affect BP. We assessed the effects of childhood obesity prevention programs on BP in children in developed countries. METHODS AND

resultsWe searched databases up to April 22, 2013, for relevant randomized, controlled trials, quasi-experimental studies, and natural experiments. Studies were included if they applied a diet or physical activity intervention(s) and were followed for ≥ 1 year (or ≥ 6 months for school-based intervention studies); they were excluded if they targeted only overweight/obese subjects or those with a medical condition. In our meta-analysis, intervention effects were calculated for systolic BP and diastolic BP with the use of weighted random-effects models. Of the 23 included intervention studies (involving 18 925 participants), 21 involved a school setting. Our meta-analysis included 19 studies reporting on systolic BP and 18 on diastolic BP. The pooled intervention effect was -1.64 mm Hg (95% confidence interval, -2.56 to -0.71; P=0.001) for systolic BP and -1.44 mm Hg (95% confidence interval, -2.28 to -0.60; P=0.001) for diastolic BP. The combined diet and physical activity interventions led to a significantly greater reduction in both systolic BP and diastolic BP than the diet-only or physical activity-only intervention. Thirteen interventions (46%) had a similar effect on both adiposity-related outcomes and BP, whereas 11 interventions (39%) showed a significant desirable effect on BP but not on adiposity-related outcomes.

conclusionsObesity prevention programs have a moderate effect on reducing BP, and those targeting both diet and physical activity seem to be more effective.

Indexed as

Blood PressureChildHumansHypertensionLife StyleObesityRisk Reduction Behaviorblood pressuremeta-analysisobesitypediatricsprevention

Identifiers

PMID24552832
PMCPMC4346224
OpenAlexW2100160949

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.