ArticleInflammatory bowel diseases2014
Venous thromboembolism in patients with inflammatory bowel diseases: a case-control study of risk factors.
Article in Inflammatory bowel diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Anti-tumor Necrosis Factor Alpha Versus Corticosteroids: A 3-fold Difference in the Occurrence of Venous Thromboembolism in Inflammatory Bowel Disease－A Systematic Review and Meta-analysis.Journal of Crohn's & colitis · 2024Pooled it
- Risk of venous thromboembolism in children and adolescents with inflammatory bowel disease: A systematic review and meta-analysis.World journal of gastroenterology · 2022Pooled it
- Venous thrombotic events in psoriasis patients: a systematic review with meta-analysis.Annals of medicine · 2021Pooled it
- Impact of venous thromboembolism on mortality in hospitalized patients with inflammatory bowel disease: analysis of the MIMIC-IV database, 2008 to 2022.BMC gastroenterology · 2025Article
- Exploring the genetic basis between inflammatory bowel disease and venous thromboembolism.Thrombosis journal · 2025Article
- Effectiveness and safety of prophylactic anticoagulation among hospitalized patients with inflammatory bowel disease.Blood advances · 2024Article
- Venous Thromboembolism in Patients with Inflammatory Bowel Disease.Journal of clinical medicine · 2023Review
- Rescue Therapy for Acute Severe Ulcerative Colitis: A Case Report.Gastroenterology & hepatology · 2023Article
- Prevalence of cerebrovascular accidents in patients with ulcerative colitis in a single academic health system.Scientific reports · 2022Article
- Real-World Insurance Claims Analysis of Venous Thromboembolism in Japanese Patients with Inflammatory Bowel Disease.Digestive diseases and sciences · 2022Article
- Article
- Inflammatory Bowel Disease: An Indication to Screen for Thrombophilia?Diseases (Basel, Switzerland) · 2022Review
- Venous and arterial thromboembolism in patients with inflammatory bowel diseases.World journal of gastroenterology · 2021Review
- Incidence and risk factors for venous thrombosis among patients with inflammatory bowel disease in China: a multicenter retrospective study.Intestinal research · 2021Article
- Genetic Variants of RPL5 and RPL9 Genes among Saudi Patients Diagnosed with Thrombosis.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2021Article
- Risk of venous thromboembolism in immune-mediated inflammatory diseases: a UK matched cohort study.RMD open · 2020Observational
- Thromboprophylaxis for Hospitalized Patients with Inflammatory Bowel Disease-Are We There Yet?Journal of clinical medicine · 2020Article
- Minor Hematochezia Decreases Use of Venous Thromboembolism Prophylaxis in Patients with Inflammatory Bowel Disease.Inflammatory bowel diseases · 2020Article
- Comorbidities in adolescents with inflammatory bowel disease: findings from a population-based cohort study.Pediatric research · 2020Article
- Recurrent Unprovoked Venous Thrombosis (Cerebral Sinus Thrombosis and Mesenteric Vein Thrombosis) in Young Patient with Crohn's Disease: A Case Report and Review.Case reports in gastrointestinal medicine · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundInflammatory bowel disease (IBD) is a well-known risk factor for venous thromboembolism (VTE). Existing guidelines for thromboprophylaxis in hospitalized patients do not extend to other clinical scenarios that may also be associated with VTE risk. Our aim was to estimate the fraction of VTE events in patients with IBD that could be prevented.
methodsA retrospective analysis assessed all patients with IBD diagnosed with VTE at a single academic medical center from 2002 to 2012. Confirmed cases were analyzed for VTE risk factors, inpatient status, the use of deep venous thrombosis prophylaxis, and when applicable the reason for omission of prophylaxis. IBD VTE cases were compared with age- and sex-matched non-IBD VTE controls with regards to risk factors and potential opportunities for VTE prevention.
resultsThere were 204 patients with IBD (108 ulcerative colitis, 96 Crohn's disease) diagnosed with VTE (110 deep venous thrombosis, 66 pulmonary embolism, 27 intra-abdominal thromboses, and 1 other). One-third of the VTE events occurred in hospitalized patients. Two-third of the medical inpatients and 44% of surgical inpatients who developed VTE did not receive prophylaxis. Importantly, 129 VTE events occurred in outpatients. The proportion of outpatients hospitalized within 4 weeks of developing venous thrombosis was higher in patients with IBD than non-IBD controls (33% versus 15%, P = 0.0003). One-third (36%) of patients were experiencing ambulatory disease flares at the time of VTE diagnosis.
conclusionsA substantial portion of VTE events in patients with IBD occurred in clinical scenarios is not routinely recommended for thromboprophylaxis. Further investigation of primary prophylaxis for patients with IBD in high-risk outpatients may be warranted.
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