Evidence map›Paper›PMID 24552683›Full record

ReviewThe Journal of investigative dermatology2014

Smuggling across the border: how arthropod-borne pathogens evade and exploit the host defense system of the skin.

Quentin Bernard, Benoit Jaulhac, Nathalie Boulanger

Abstract readReview
PubMed Publisher
In one paragraph

Review in The Journal of investigative dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Adaptive immunity inApplied and environmental microbiology · 2024
    Article
  3. Article
  4. Tick saliva and its role in pathogen transmission.Wiener klinische Wochenschrift · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Plasticity in early immune evasion strategies of a bacterial pathogen.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Quentin BernardEA7290, Virulence Bacterienne Precoce, Groupe Borréliose de Lyme, Institut de Bacteriologie, Universite de Strasbourg, Strasbourg, France.
Benoit JaulhacEA7290, Virulence Bacterienne Precoce, Groupe Borréliose de Lyme, Institut de Bacteriologie, Universite de Strasbourg, Strasbourg, France; Centre National de Reference Borrelia, Centre Hospitalier Universitaire, Strasbourg, France.
Nathalie BoulangerEA7290, Virulence Bacterienne Precoce, Groupe Borréliose de Lyme, Institut de Bacteriologie, Universite de Strasbourg, Strasbourg, France; Centre National de Reference Borrelia, Centre Hospitalier Universitaire, Strasbourg, France. Electronic address: nboulanger@unistra.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin is a critical barrier between hosts and pathogens in arthropod-borne diseases. It harbors many resident cells and specific immune cells to arrest or limit infections by secreting inflammatory molecules or by directly killing pathogens. However, some pathogens are able to use specific skin cells and arthropod saliva for their initial development, to hide from the host immune system, and to establish persistent infection in the vertebrate host. A better understanding of the initial mechanisms taking place in the skin should allow the development of new strategies to fight these vector-borne pathogens that are spread worldwide and are of major medical importance.

Indexed as

Arthropod VectorsImmune SystemAnimalsArthropodsHumansInfectionsSkin

Identifiers

PMID24552683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.