Evidence map›Paper›PMID 24551400›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2013

Temporal abstraction-based clinical phenotyping with Eureka!

Andrew R Post, Tahsin Kurc, Richie Willard, Himanshu Rathod, Michel Mansour, Akshatha Kalsanka Pai, William M Torian, Sanjay Agravat, Suzanne Sturm, Joel H Saltz

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. A Method for EHR Phenotype Management in an i2b2 Data Warehouse.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  5. Article
  6. Learning Optimal Individualized Treatment Rules from Electronic Health Record Data.Proceedings. IEEE International Conference on Healthcare Informatics · 2016
    Article
  7. A Modular Architecture for Electronic Health Record-Driven Phenotyping.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrew R PostDept. of Biomedical Informatics, Emory University, Atlanta, GA.
Tahsin KurcDept. of Biomedical Informatics, Emory University, Atlanta, GA.
Richie WillardDept. of Biomedical Informatics, Emory University, Atlanta, GA.
Himanshu RathodDept. of Biomedical Informatics, Emory University, Atlanta, GA.
Michel MansourDept. of Biomedical Informatics, Emory University, Atlanta, GA.
Akshatha Kalsanka PaiDept. of Biomedical Informatics, Emory University, Atlanta, GA.
William M TorianDept. of Biomedical Informatics, Emory University, Atlanta, GA.
Sanjay AgravatDept. of Biomedical Informatics, Emory University, Atlanta, GA.
Suzanne SturmDept. of Biomedical Informatics, Emory University, Atlanta, GA.
Joel H SaltzDept. of Biomedical Informatics, Emory University, Atlanta, GA.

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
The CardioVascular Research GridR24HL085343 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI WINSLOW, RAIMOND LESTER · 2007 to 2015
$19.4M
Minority Health-GRID Network: A Genomics Resource for Health Disparity ResearchRC4MD005964 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI DAVIS, ROBERT LOWELL, NICKERSON, DEBORAH A · 2010 to 2010
$13.3M
Image Mining for Comparative Analysis of Expression Patterns in Tissue MicroarrayR01LM009239 · NLM · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI FORAN, DAVID J, SALTZ, JOEL H. · 2007 to 2016
$4.5M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalKL2TR000455 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$2.9M
Atlanta Clinical and Translational Science Institute (KL2)KL2RR025009 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$2.9M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalTL1TR000456 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$1.2M
Atlanta Clinical and Translational Science Institute (TL1)TL1RR025010 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$1.1M
NCATS NIH HHS KL2 TR000455NCATS NIH HHS TL1 TR000456NCATS NIH HHS UL1 TR000454NCRR NIH HHS KL2 RR025009NCRR NIH HHS TL1 RR025010NCRR NIH HHS UL1 RR025008NHLBI NIH HHS R24 HL085343NIMHD NIH HHS RC4 MD005964NIMHD NIH HHS RC4MD005964NLM NIH HHS R01 LM009239
6 · The paper itself

Abstract

Temporal abstraction, a method for specifying and detecting temporal patterns in clinical databases, is very expressive and performs well, but it is difficult for clinical investigators and data analysts to understand. Such patterns are critical in phenotyping patients using their medical records in research and quality improvement. We have previously developed the Analytic Information Warehouse (AIW), which computes such phenotypes using temporal abstraction but requires software engineers to use. We have extended the AIW's web user interface, Eureka! Clinical Analytics, to support specifying phenotypes using an alternative model that we developed with clinical stakeholders. The software converts phenotypes from this model to that of temporal abstraction prior to data processing. The model can represent all phenotypes in a quality improvement project and a growing set of phenotypes in a multi-site research study. Phenotyping that is accessible to investigators and IT personnel may enable its broader adoption.

Indexed as

AlgorithmsElectronic Health RecordsPattern Recognition, AutomatedSoftwareData MiningHumansKnowledge BasesTime

Identifiers

PMID24551400
PMCPMC3900137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.