Evidence map›Paper›PMID 24551388›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2013

A natural language processing algorithm to define a venous thromboembolism phenotype.

Eugenia R McPeek Hinz, Lisa Bastarache, Joshua C Denny

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Prediction and Diagnosis of Venous Thromboembolism Using Artificial Intelligence Approaches: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eugenia R McPeek HinzDepartment of Pediatrics Duke University Medical Center, Durham NC.
Lisa BastaracheDepartments of Biomedical Informatics, Nashville, TN.
Joshua C DennyDepartments of Biomedical Informatics, Nashville, TN ; Medicine Vanderbilt University School of Medicine, Nashville, TN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep venous thrombosis and pulmonary embolism are diseases associated with significant morbidity and mortality. Known risk factors are attributed for only slight majority of venous thromboembolic disease (VTE) with the remainder of risk presumably related to unidentified genetic factors. We designed a general purpose Natural Language (NLP) algorithm to retrospectively capture both acute and historical cases of thromboembolic disease in a de-identified electronic health record. Applying the NLP algorithm to a separate evaluation set found a positive predictive value of 84.7% and sensitivity of 95.3% for an F-measure of 0.897, which was similar to the training set of 0.925. Use of the same algorithm on problem lists only in patients without VTE ICD-9s was found to be the best means of capturing historical cases with a PPV of 83%. NLP of VTE ICD-9 positive cases and non-ICD-9 positive problem lists provides an effective means for capture of both acute and historical cases of venous thromboembolic disease.

Indexed as

AlgorithmsElectronic Health RecordsNatural Language ProcessingPulmonary EmbolismVenous ThrombosisHumansInformation Storage and RetrievalInternational Classification of DiseasesPhenotypeVenous Thromboembolism

Identifiers

PMID24551388
PMCPMC3900229

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.