Evidence map›Paper›PMID 24551375›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2013

Lessons learned in replicating data-driven experiments in multiple medical systems and patient populations.

Samantha Kleinberg, Noémie Elhadad

Abstract readValidation Study
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. How causal information affects decisions.Cognitive research: principles and implications · 2020
    Article
  2. Replicability, Reproducibility, and Agent-based Simulation of Interventions.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2017
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. HARVEST, a longitudinal patient record summarizer.Journal of the American Medical Informatics Association : JAMIA · 2015
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Samantha KleinbergStevens Institute of Technology, Hoboken, NJ;
Noémie ElhadadColumbia University, New York, NY.

Funding

NLM NIH HHS HHSN276201000024CPHS HHS 1019343
6 · The paper itself

Abstract

Electronic health records are an increasingly important source of data for research, allowing for large-scale longitudinal studies on the same population that is being treated. Unlike in controlled studies, though, these data vary widely in quality, quantity, and structure. In order to know whether algorithms can accurately uncover new knowledge from these records, or whether findings can be extrapolated to new populations, they must be validated. One approach is to conduct the same study in multiple sites and compare results, but it is a challenge to determine whether differences are due to artifacts of the medical process, population differences, or failures of the methods used. In this paper we describe the results of replicating a data-driven experiment to infer possible causes of congestive heart failure and their timing using data from two medical systems and two patient populations. We focus on the difficulties faced in this type of work, lessons learned, and recommendations for future research.

Indexed as

Data MiningMedical Records Systems, ComputerizedCausalityDisease ProgressionElectronic Health RecordsHeart FailureHumansInternational Classification of DiseasesNatural Language Processing

Identifiers

PMID24551375
PMCPMC3900216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.