Evidence map›Paper›PMID 24551346›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2013

Ontological approach to reduce complexity in polypharmacy.

Susan Farrish, Adela Grando

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Susan FarrishUnited States Air Force, Air Force Medical Support Agency, Medical Informatics Division, Joint Base San Antonio Lackland, Texas.
Adela GrandoDivision of Biomedical Informatics, University of California San Diego, La Jolla, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients that are on many medications are often non-compliant due to the complexity of the medication regimen; consequently, a patient that is non-compliant can have poor medical outcomes. Providers are not always aware of the complexity of their patient's prescriptions. Methods have been developed to calculate the complexity for a patient's regimen but there are no widely available automated tools that will do this for a provider. Given that ontologies are known to provide well-principled, sharable, setting-independent and machine-interpretable declarative specification frameworks for modeling and reasoning on biomedical problems, we have explored their use in the context of reducing medication complexity. Previously we proposed an Ontology for modeling drug-related knowledge and a repository for complexity scoring. Here we tested the Ontology with patient data from the University of California San Diego Epic database, and we built a decision aide that computes the complexity and recommends changes to reduce the complexity, if needed.

Indexed as

Biological OntologiesDecision Support TechniquesDrug Therapy, Computer-AssistedPolypharmacyDrug PrescriptionsHumansMedication AdherenceProgramming LanguagesTerminology as Topic

Identifiers

PMID24551346
PMCPMC3900187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.