Evidence map›Paper›PMID 24551268›Full record

ReviewInternational journal of clinical and experimental pathology2014

Treg cells: a potential regulator for IL-22 expression?

Shuman Lin, Xuyan Yang, Dian Liang, Song Guo Zheng

Abstract readReview
In one paragraph

Review in International journal of clinical and experimental pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. A protocol for humanized synovitis mice model.American journal of clinical and experimental immunology · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Role of interleukin-22 in inflammatory bowel disease.World journal of gastroenterology · 2014
    Review
  17. Computational modeling of heterogeneity and function of CD4+ T cells.Frontiers in cell and developmental biology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shuman LinMedical College at Sun Yat‑Sen University Guangzhou, 510008, P. R. China.
Xuyan YangDepartment of Rheumatology, Second Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, 310009, P. R. China.
Dian LiangMedical College at Sun Yat‑Sen University Guangzhou, 510008, P. R. China.
Song Guo ZhengDivision of Rheumatology, Department of Medicine at Penn State University Hershey College of Medicine Hershey, 17033, USA ; Institute of Immunology, Shanghai East Hospital at Tongji University Shanghai, 200120, P. R. China.

Funding

Therapeutic immunoregulation mediated by TGF-??-induced iTregs in autoimmune arthR01AR059103 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JARJOUR, WAEL N · 2010 to 2020
$3.9M
Generation of Regulatory T cells ex-vivo for the treatment of systemic lupus erytR43AI084359 · NIAID · EXCELL THERAPEUTICS, LLC · PI O'NEIL, DAVID · 2011 to 2011
$245k
NIAID NIH HHS AI-084359NIAID NIH HHS R43 AI084359NIAMS NIH HHS AR-059103NIAMS NIH HHS R01 AR059103
6 · The paper itself

Abstract

Inteleurkin-22 (IL-22) is a IL-10 family cytokine member and is mainly produced by innate lymphoid cells (ILCs), Th17 cells, and Th22 cells. Previous studies have indicated that IL-23 and several transcription factors, including STAT3, RORγt, and the AhR are important stimulus. Recently, there is emerging evidence that Tregs can regulate IL-22 expression. In the review, we discuss the updated advancement on Tregs function and its regulatory role on IL-22 expression.

Indexed as

AnimalsCell CommunicationGene Expression RegulationHumansImmunity, InnateInterleukin-22InterleukinsSignal TransductionT-Lymphocytes, Helper-InducerT-Lymphocytes, RegulatoryInterleukin-22Interleukinsinnate immune cellsInterleukin-22regulatory (Treg) cellsT helper cells

Identifiers

PMID24551268
PMCPMC3925892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.