Evidence map›Paper›PMID 24551183›Full record

ArticlePloS one2014

Allergens and β-glucans in dutch homes and schools: characterizing airborne levels.

Esmeralda J M Krop, José H Jacobs, Ingrid Sander, Monika Raulf-Heimsoth, Dick J J Heederik

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Interventions for autumn exacerbations of asthma in children.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Environmental Exposures Impact Pediatric Asthma Within the School Environment.Immunology and allergy clinics of North America · 2022
    Review
  9. Comparing the concentration levels of allergens and endotoxins in employees' homes and offices.International archives of occupational and environmental health · 2022
    Article
  10. Article
  11. Indoor Air Quality Levels in Schools: Role of Student Activities and No Activities.International journal of environmental research and public health · 2020
    Article
  12. Review
  13. Article
  14. Article
  15. Asthma and Allergies in the School Environment.Clinical reviews in allergy & immunology · 2019
    Review
  16. Airborne Rodent Allergen Levels in Dutch Households: A Pilot Study.International journal of environmental research and public health · 2019
    Article
  17. Bedroom Allergen Exposure Beyond House Dust Mites.Current allergy and asthma reports · 2018
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Esmeralda J M KropInstitute for Risk Assessment Sciences, Utrecht University, Division of Environmental Epidemiology, Utrecht, The Netherlands.
José H JacobsInstitute for Risk Assessment Sciences, Utrecht University, Division of Environmental Epidemiology, Utrecht, The Netherlands.
Ingrid SanderInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany.
Monika Raulf-HeimsothInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany.
Dick J J HeederikInstitute for Risk Assessment Sciences, Utrecht University, Division of Environmental Epidemiology, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndoor air quality has an effect on respiratory health. Children are more vulnerable to a decreased indoor air quality as their lungs are still developing. We measured levels of allergens and β-(1,3)-glucans in 19 school buildings and determined whether measured levels could be reproduced. School levels were compared to those in 169 homes and the effect of building characteristics on both home and school exposure was explored.

methodsElectrostatic Dust fall Collectors were placed in school buildings for 8 weeks and in homes for 2 weeks to collect settled airborne dust. Cat, dog, and mouse allergen levels, domestic mite antigen levels and β-(1,3)-glucans were measured in the extracts from the collectors. Results were corrected for sampling duration. Using questionnaire data, relations between measured levels and building and classroom characteristics were explored.

resultsIn schools, exposure levels were highest in classrooms and were influenced by the socioeconomic status of the children, the season measurements were performed, moisture status of the building and pet ownership. Repeated measurements in different seasons and over the years showed significantly different levels. Home exposure was influenced by socioeconomic status, occupancy and pet ownership. Domestic mite antigen was found in higher levels in extracts from homes compared to schools while pet allergen levels were 13 times higher in schools compared to homes without pets. For mouse allergen overall levels of exposure were low but still two times higher in schools compared to homes. Levels of β-(1,3)-glucans were also approximately two times higher in schools than in homes.

conclusionExposure levels of several allergens and β-(1,3)-glucans in schools differ over time and are higher than in homes. For children, exposure levels measured at school could contribute to their total exposure as especially animal allergen levels can be much higher in schools compared to homes.

Indexed as

Environmental MonitoringSchoolsAir PollutantsAir Pollution, IndoorAllergensAnimalsbeta-GlucansCatsDogsHumansMiceMultivariate AnalysisNetherlandsSeasonsAir PollutantsAllergensbeta-Glucans

Identifiers

PMID24551183
PMCPMC3925184

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.