ArticlePloS one2014
Starvation induces phenotypic diversification and convergent evolution in Vibrio vulnificus.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Comparative genomics reveals specialization and divergent virulence potential inApplied and environmental microbiology · 2025Article
- Denitrification by Bradyrhizobia under Feast and Famine and the Role of the bc1 Complex in Securing Electrons for NApplied and environmental microbiology · 2023Article
- Survival Characteristics and Transcriptomic Analyses Reveal the Adaptive Response of the Aquatic Pathogen Non-O1/O139 Vibrio cholerae to Starvation Stress.Microbiology spectrum · 2022Article
- Article
- Monitoring the Starvation-Survival Response ofMicroorganisms · 2022Article
- The Effect of Visible Light on Cell Envelope Subproteome duringMicroorganisms · 2021Article
- Article
- Draft Genome Sequence of Vibrio vulnificus 86573B, a Bacterium Isolated from Diseased Tilapia in Taiwan.Microbiology resource announcements · 2018Article
- Molecular Basis of Stationary Phase Survival and Applications.Frontiers in microbiology · 2017Review
- Changes in the Vibrio harveyi Cell Envelope Subproteome During Permanence in Cold Seawater.Microbial ecology · 2016Article
- The Ecological Coherence of Temperature and Salinity Tolerance Interaction and Pigmentation in a Non-marineFrontiers in microbiology · 2016Article
- Unveiling the Metabolic Pathways Associated with the Adaptive Reduction of Cell Size During Vibrio harveyi Persistence in Seawater Microcosms.Microbial ecology · 2015Article
- Complete Genome Sequence of Vibrio vulnificus 93U204, a Bacterium Isolated from Diseased Tilapia in Taiwan.Genome announcements · 2014Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Starvation is a common stress experienced by bacteria living in natural environments and the ability to adapt to and survive intense stress is of paramount importance for any bacterial population. A series of starvation experiments were conducted using V. vulnificus 93U204 in phosphate-buffered saline and seawater. The starved population entered the death phase during the first week and approximately 1% of cells survived. After that the population entered a long-term stationary phase, and could survive for years. Starvation-induced diversification (SID) of phenotypes was observed in starved populations and phenotypic variants (PVs) appeared in less than 8 days. The cell density, rather than the population size, had a major effect on the extent of SID. SID was also observed in strain YJ016, where it evolved at a faster pace. PVs appeared to emerge in a fixed order: PV with reduced motility, PV with reduced proteolytic activity, and PV with reduced hemolytic activity. All of the tested PVs had growth advantages in the stationary phase phenotypes and increased fitness compared with 93U204 cells in co-culture competition experiments, which indicates that they had adapted to starvation. We also found that SID occurred in natural seawater with a salinity of 1%-3%, so this mechanism may facilitate bacterial adaptation in natural environments.
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