Evidence map›Paper›PMID 24551056›Full record

ArticlePloS one2014

BiNA: a visual analytics tool for biological network data.

Andreas Gerasch, Daniel Faber, Jan Küntzer, Peter Niermann, Oliver Kohlbacher, Hans-Peter Lenhof, Michael Kaufmann

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Molecular networks in Network Medicine: Development and applications.Wiley interdisciplinary reviews. Systems biology and medicine · 2020
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
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  11. Review
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  13. Article
  14. Improving collaboration by standardization efforts in systems biology.Frontiers in bioengineering and biotechnology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andreas GeraschAlgorithmics, Department for Computer Science, University of Tübingen, Tübingen, Germany ; Applied Bioinformatics, Center for Bioinformatics, Quantitative Biology Center, and Department for Computer Science, University of Tübingen, Tübingen, Germany.
Daniel FaberAlgorithmics, Department for Computer Science, University of Tübingen, Tübingen, Germany.
Jan KüntzerRoche Diagnostics GmbH, Pharma Research and Early Development Informatics, Penzberg, Germany.
Peter NiermannApplied Bioinformatics, Center for Bioinformatics, Quantitative Biology Center, and Department for Computer Science, University of Tübingen, Tübingen, Germany.
Oliver KohlbacherApplied Bioinformatics, Center for Bioinformatics, Quantitative Biology Center, and Department for Computer Science, University of Tübingen, Tübingen, Germany.
Hans-Peter LenhofCenter for Bioinformatics, Saarland University, Saarbrücken, Germany.
Michael KaufmannAlgorithmics, Department for Computer Science, University of Tübingen, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interactive visual analysis of biological high-throughput data in the context of the underlying networks is an essential task in modern biomedicine with applications ranging from metabolic engineering to personalized medicine. The complexity and heterogeneity of data sets require flexible software architectures for data analysis. Concise and easily readable graphical representation of data and interactive navigation of large data sets are essential in this context. We present BiNA--the Biological Network Analyzer--a flexible open-source software for analyzing and visualizing biological networks. Highly configurable visualization styles for regulatory and metabolic network data offer sophisticated drawings and intuitive navigation and exploration techniques using hierarchical graph concepts. The generic projection and analysis framework provides powerful functionalities for visual analyses of high-throughput omics data in the context of networks, in particular for the differential analysis and the analysis of time series data. A direct interface to an underlying data warehouse provides fast access to a wide range of semantically integrated biological network databases. A plugin system allows simple customization and integration of new analysis algorithms or visual representations. BiNA is available under the 3-clause BSD license at http://bina.unipax.info/.

Indexed as

Database Management SystemsGene Regulatory NetworksMetabolic Networks and PathwaysAlgorithmsComputer GraphicsDatabases, FactualData MiningHumansProtein Interaction Mapping

Identifiers

PMID24551056
PMCPMC3923765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.