ArticlePloS one2014
Phase of shear vibrations within cochlear partition leads to activation of the cochlear amplifier.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- An alternative pathway for delivery of power by outer hair cells to cochlear traveling waves.Hearing research · 2026Article
- Intracochlear overdrive: Characterizing nonlinear wave amplification in the mouse apex.The Journal of the Acoustical Society of America · 2023Article
- Overturning the mechanisms of cochlear amplification via area deformations of the organ of Corti.The Journal of the Acoustical Society of America · 2022Article
- Link between stimulus otoacoustic emissions fine structure peaks and standing wave resonances in a cochlear model.The Journal of the Acoustical Society of America · 2022Article
- The interplay of organ-of-Corti vibrational modes, not tectorial- membrane resonance, sets outer-hair-cell stereocilia phase to produce cochlear amplification.Hearing research · 2020Review
- Modeling signal propagation in the human cochlea.The Journal of the Acoustical Society of America · 2017Article
- Two-Tone Suppression of Simultaneous Electrical and Mechanical Responses in the Cochlea.Biophysical journal · 2016Article
- Gating of Acoustic Transducer Channels Is Shaped by Biomechanical Filter Processes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Intracochlear Scala Media Pressure Measurement: Implications for Models of Cochlear Mechanics.Biophysical journal · 2015Article
- Filtering of acoustic signals within the hearing organ.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Since Georg von Bekesy laid out the place theory of the hearing, researchers have been working to understand the remarkable properties of mammalian hearing. Because access to the cochlea is restricted in live animals, and important aspects of hearing are destroyed in dead ones, models play a key role in interpreting local measurements. Wentzel-Kramers-Brillouin (WKB) models are attractive because they are analytically tractable, appropriate to the oblong geometry of the cochlea, and can predict wave behavior over a large span of the cochlea. Interest in the role the tectorial membrane (TM) plays in cochlear tuning led us to develop models that directly interface the TM with the cochlear fluid. In this work we add an angled shear between the TM and reticular lamina (RL), which serves as an input to a nonlinear active force. This feature plus a novel combination of previous work gives us a model with TM-fluid interaction, TM-RL shear, a nonlinear active force and a second wave mode. The behavior we get leads to the conclusion the phase between the shear and basilar membrane (BM) vibration is critical for amplification. We show there is a transition in this phase that occurs at a frequency below the cutoff, which is strongly influenced by TM stiffness. We describe this mechanism of sharpened BM velocity profile, which demonstrates the importance of the TM in overall cochlear tuning and offers an explanation for the response characteristics of the Tectb mutant mouse.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.