Evidence map›Paper›PMID 24550833›Full record

ReviewFrontiers in physiology2013

Effects of physical activity on endothelial progenitor cells (EPCs).

Chiara De Biase, Roberta De Rosa, Rossella Luciano, Stefania De Luca, Ernesto Capuano, Bruno Trimarco, Gennaro Galasso

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

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  5. Endothelial Progenitor Cells in Life, Pregnancy and Disease.Expert reviews in molecular medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chiara De BiaseDepartment of Advanced Biomedical Sciences, "Federico II" University of Naples Naples, Italy.
Roberta De RosaDepartment of Advanced Biomedical Sciences, "Federico II" University of Naples Naples, Italy.
Rossella LucianoDepartment of Advanced Biomedical Sciences, "Federico II" University of Naples Naples, Italy.
Stefania De LucaDepartment of Advanced Biomedical Sciences, "Federico II" University of Naples Naples, Italy.
Ernesto CapuanoDepartment of Advanced Biomedical Sciences, "Federico II" University of Naples Naples, Italy.
Bruno TrimarcoDepartment of Advanced Biomedical Sciences, "Federico II" University of Naples Naples, Italy.
Gennaro GalassoDepartment of Advanced Biomedical Sciences, "Federico II" University of Naples Naples, Italy.
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity has a therapeutic role in cardiovascular disease (CVD), through its beneficial effects on endothelial function and cardiovascular system. Circulating endothelial progenitor cells (EPCs) are bone marrow (BM) derived cells that represent a novel therapeutic target in CVD patients, because of their ability to home to sites of ischemic injury and repair the damaged vessels. Several studies show that physical activity results in a significant increase in circulating EPCs, and, in particular, there are some evidence of the beneficial exercise-induced effects on EPCs activity in CVD settings, including coronary artery disease (CAD), heart failure (HF), and peripheral artery disease (PAD). The aim of this paper is to review the current evidence about the beneficial effects of physical exercise on endothelial function and EPCs levels and activity in both healthy subjects and patients with CVD.

Indexed as

bone marrowcardiovascular diseasecoronary artery diseaseendothelial progenitor cellphysical activity

Identifiers

PMID24550833
PMCPMC3909827
OpenAlexW2120697449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.