ArticleFrontiers in human neuroscience2014
Chronic traumatic encephalopathy and other neurodegenerative proteinopathies.
Article in Frontiers in human neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Concussion and long-term cognitive impairment among professional or elite sport-persons: a systematic review.Journal of neurology, neurosurgery, and psychiatry · 2020Pooled it
- Unusual combinations of neurodegenerative pathologies with chronic traumatic encephalopathy (CTE) complicates clinical prediction of CTE.European journal of neurology · 2024Article
- Frontotemporal Dementia: Dilemma in Discrimination From Similarly Presenting Neurological and Psychiatric Conditions.Cureus · 2022Article
- Non-Targeted Metabolomics Approach Revealed Significant Changes in Metabolic Pathways in Patients with Chronic Traumatic Encephalopathy.Biomedicines · 2022Article
- Alterations of transcriptome signatures in head trauma-related neurodegenerative disorders.Scientific reports · 2020Article
- Biological links between traumatic brain injury and Parkinson's disease.Acta neuropathologica communications · 2020Review
- Interaction of APOE4 alleles and PET tau imaging in former contact sport athletes.NeuroImage. Clinical · 2020Article
- Inflammation in Traumatic Brain Injury.Journal of Alzheimer's disease : JAD · 2020Review
- A Clinicopathological Report of a 93-Year-Old Former Street Boxer With Coexistence of Chronic Traumatic Encephalopathy, Alzheimer's Disease, Dementia With Lewy Bodies, and Hippocampal Sclerosis With TDP-43 Pathology.Frontiers in neurology · 2020Article
- Elevated cerebrospinal fluid total tau in former professional athletes with multiple concussions.Neurology · 2019Article
- The Role of TDP-43 in Military-Relevant TBI and Chronic Neurodegeneration.Frontiers in neurology · 2019Review
- Comprehensive Neuropsychiatric and Cognitive Characterization of Former Professional Football Players: Implications for Neurorehabilitation.Frontiers in neurology · 2019Article
- Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity.Frontiers in neuroscience · 2019Article
- Concussion education in Canadian medical schools: a 5 year follow-up survey.BMC medical education · 2018Article
- Article
- Pathologic ThrNeurology · 2018Article
- Alzheimer's Dementia due to Suspected CTE from Subconcussive Head Impact.Case reports in neurological medicine · 2018Article
- The Inflammatory Continuum of Traumatic Brain Injury and Alzheimer's Disease.Frontiers in immunology · 2018Review
- Understanding blast-induced neurotrauma: how far have we come?Concussion (London, England) · 2017Review
- Chronic Traumatic Encephalopathy and Movement Disorders: Update.Current neurology and neuroscience reports · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
"Chronic traumatic encephalopathy" (CTE) is described as a slowly progressive neurodegenerative disease believed to result from multiple concussions. Traditionally, concussions were considered benign events and although most people recover fully, about 10% develop a post-concussive syndrome with persisting neurological, cognitive and neuropsychiatric symptoms. CTE was once thought to be unique to boxers, but it has now been observed in many different athletes having suffered multiple concussions as well as in military personal after repeated blast injuries. Much remains unknown about the development of CTE but its pathological substrate is usually tau, similar to that seen in Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD). The aim of this "perspective" is to compare and contrast clinical and pathological CTE with the other neurodegenerative proteinopathies and highlight that there is an urgent need for understanding the relationship between concussion and the development of CTE as it may provide a window into the development of a proteinopathy and thus new avenues for treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.