ReviewAmerican journal of Alzheimer's disease and other dementias2014
Diagnosis and prognosis in idiopathic normal pressure hydrocephalus.
Review in American journal of Alzheimer's disease and other dementias, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 52 citations in OpenAlex.
- Diagnostic performance of black tent sign on 3D T2 SPACE in the diagnosis of idiopathic normal-pressure hydrocephalus.Japanese journal of radiology · 2025Article
- Peripheral immunity patterns, imaging features, and clinical outcomes in patients with gait impairment and ventriculomegaly on brain MRI.Frontiers in aging neuroscience · 2025Article
- Increasing incidence of normal pressure hydrocephalus in Germany: an analysis of the Federal Statistical Office Database from 2005 to 2022.Scientific reports · 2024Article
- Peripheral immunity changes are associated with neurodegeneration and worse clinical outcome in idiopathic normal pressure hydrocephalus.European journal of neurology · 2024Article
- CSF Biomarkers Predict Gait Outcomes in Idiopathic Normal Pressure Hydrocephalus.Neurology. Clinical practice · 2022Article
- Decreased Craniocervical CSF Flow in Patients with Normal Pressure Hydrocephalus: A Pilot Study.AJNR. American journal of neuroradiology · 2022Article
- Asymmetric rapidly progressive idiopathic normal-pressure hydrocephalus: description of a case.Journal of neurology · 2022Article
- Lumbar and ventricular CSF concentrations of extracellular matrix proteins before and after shunt surgery in idiopathic normal pressure hydrocephalus.Fluids and barriers of the CNS · 2021Article
- Structural volumetry in NPH diagnostics and treatment-future or dead end?Neurosurgical review · 2021Article
- Outcomes of Ventriculoperitoneal Shunt in Patients With Idiopathic Normal-Pressure Hydrocephalus 2 Years After Surgery.Frontiers in surgery · 2021Article
- The Pathogenesis Based on the Glymphatic System, Diagnosis, and Treatment of Idiopathic Normal Pressure Hydrocephalus.Clinical interventions in aging · 2021Review
- In vivo Characterization of Biochemical Variants of Amyloid-β in Subjects with Idiopathic Normal Pressure Hydrocephalus and Alzheimer's Disease Neuropathological Change.Journal of Alzheimer's disease : JAD · 2021Article
- Normal pressure hydrocephalus-an overview of pathophysiological mechanisms and diagnostic procedures.Neurosurgical review · 2020Review
- Cerebrospinal fluid biomarkers profile of idiopathic normal pressure hydrocephalus.Journal of neural transmission (Vienna, Austria : 1996) · 2018Review
- Decreased Expression of hsa-miR-4274 in Cerebrospinal Fluid of Normal Pressure Hydrocephalus Mimics with Parkinsonian Syndromes.Journal of Alzheimer's disease : JAD · 2017Article
- Intracranial hypotension-like syndrome after a spinal tap test performed for idiopathic normal pressure hydrocephalus.American journal of Alzheimer's disease and other dementias · 2015Article
- [MRI in dementia-type diseases].Der Radiologe · 2015Article
- A clinical and biochemical analysis in the differential diagnosis of idiopathic normal pressure hydrocephalus.Frontiers in neurology · 2015Article
- Feasibility of action observation effect on gait and mobility in idiopathic normal pressure hydrocephalus patients.Dementia & neuropsychologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic normal pressure hydrocephalus (iNPH) is a communicating hydrocephalus, of unknown pathophysiology, characterized by the classical triad of dementia, urinary incontinence, and ataxia. The most popular treatment option is shunt surgery, although it is not a cure. The diagnosis of the disorder is challenging as it may mimic a lot of other neurological conditions and has no distinct biomarker. It becomes even more challenging as majority of the cases are diagnosed by invasive cerebrospinal fluid (CSF) removal tests. However, a careful history taking, a keen and detailed physical examination, and pertinent imaging studies can lead to an early diagnosis. The gait symptoms respond the most to surgery. The predictors deciding the postsurgical prognosis has been discussed. Improved shunting modalities and novel shunt materials with valve adjustments have improved the precision of the shunting procedures. Still we have lot more to achieve in terms of early diagnosis and definitive management of iNPH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.