Evidence map›Paper›PMID 24550068›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2014

Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation.

Basma Hashmi, Lauren D Zarzar, Tadanori Mammoto, Akiko Mammoto, Amanda Jiang, Joanna Aizenberg, Donald E Ingber

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Responsive-Hydrogel Aquabots.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  6. Review
  7. Next-Generation Biomaterials for Culture and Manipulation of Stem Cells.Cold Spring Harbor perspectives in biology · 2020
    Article
  8. Article
  9. Article
  10. From mechanobiology to developmentally inspired engineering.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Basma HashmiWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA; Harvard School of Engineering and Applied Sciences, Cambridge, MA, 02138, USA.
Lauren D Zarzar
Tadanori Mammoto
Akiko Mammoto
Amanda Jiang
Joanna Aizenberg
Donald E Ingber

Funding

Micromechanical Determinants of Organ Design and Engineering (SysCODE 6 of 10)RL1DE019023 · NIDCR · BOSTON CHILDREN'S HOSPITAL · PI INGBER, DONALD E · 2007 to 2011
$2.9M
NIDCR NIH HHS RL1 DE019023NIDCR NIH HHS RL1DE019023
6 · The paper itself

Abstract

A biologically inspired thermoresponsive polymer has been developed that mechanically induces tooth differentiation in vitro and in vivo by promoting mesenchymal cell compaction as seen in each pore of the scaffold. This normally occurs during the physiological mesenchymal condensation response that triggers tooth formation in the embryo.

Indexed as

TemperatureAcrylic ResinsAnimalsBiocompatible MaterialsBiomimetic MaterialsBone Morphogenetic Protein 4Cell DifferentiationHydrogelsKidneyMesenchymal Stem CellsMiceMSX1 Transcription FactorOligopeptidesPaired Box Transcription FactorsPAX9 Transcription FactorPorosityAcrylic ResinsBiocompatible MaterialsBmp4 protein, mouseBone Morphogenetic Protein 4glycyl-arginyl-glycyl-aspartyl-serineHydrogelsMsx1 protein, mouseMSX1 Transcription FactorOligopeptidesPaired Box Transcription FactorsPax9 protein, mousePAX9 Transcription Factorpoly-N-isopropylacrylamidebiomaterialsodontogenesispoly(N-isopropylacrylamide)scaffold engineeringthermoresponsive

Identifiers

PMID24550068
PMCPMC4146397

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.