ReviewSocial psychiatry and psychiatric epidemiology2014
The epigenome and postnatal environmental influences in psychotic disorders.
Review in Social psychiatry and psychiatric epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Stress, Dysregulation of Rhythms, and Bipolar Disorder: A Challenging Field of Research.Journal of clinical medicine · 2024Article
- Impact of psychosocial stress on facial emotion recognition in schizophrenia and controls: an experimental study in a forensic sample.Frontiers in psychiatry · 2024Article
- The role of environmental stress and DNA methylation in the longitudinal course of bipolar disorder.International journal of bipolar disorders · 2020Article
- Sensitivity to Peer Evaluation and Its Genetic and Environmental Determinants: Findings from a Population-Based Twin Study.Child psychiatry and human development · 2018Article
- Antidepressant-Like Effects of Acupuncture-Insights From DNA Methylation and Histone Modifications of Brain-Derived Neurotrophic Factor.Frontiers in psychiatry · 2018Article
- Epigenomics of Major Depressive Disorders and Schizophrenia: Early Life Decides.International journal of molecular sciences · 2017Review
- The Link Between the Immune System, Environment, and Psychosis.Schizophrenia bulletin · 2017Review
- A Novel Bio-Psychosocial-Behavioral Treatment Model in Schizophrenia.International journal of molecular sciences · 2017Review
- Novel methods in psychiatric epidemiology.Social psychiatry and psychiatric epidemiology · 2016Article
- BDNF DNA methylation changes as a biomarker of psychiatric disorders: literature review and open access database analysis.Behavioral and brain functions : BBF · 2016Review
- Ecological Interventionist Causal Models in Psychosis: Targeting Psychological Mechanisms in Daily Life.Schizophrenia bulletin · 2016Article
- Animal models of gene-environment interaction in schizophrenia: A dimensional perspective.Progress in neurobiology · 2016Review
- Perinatal Risks and Childhood Premorbid Indicators of Later Psychosis: Next Steps for Early Psychosocial Interventions.Schizophrenia bulletin · 2015Review
- Focus on psychosis.Dialogues in clinical neuroscience · 2015Review
- The expanding scope of psychiatric epidemiology in the 21st century.Social psychiatry and psychiatric epidemiology · 2014Article
- Postnatal risk environments, epigenetics, and psychosis: putting the pieces together.Social psychiatry and psychiatric epidemiology · 2014Article
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSchizophrenia spectrum disorders and bipolar spectrum disorders are the product of both heritable and non-heritable factors, the impact of which converges at different biological levels. Recent evidence from molecular approaches has provided new insights about how environmental exposures cause persistent alterations in the regulation of gene expression, particularly by so-called epigenetic mechanisms. The aim of this review is to provide an overview of findings of epigenetic studies in psychotic disorders, summarizing findings of human and animal studies on epigenetic alterations due to postnatal environmental exposures associated with psychotic disorders.
methodsElectronic and manual literature search of MEDLINE, EMBASE and PSYCHINFO, using a range of search terms around epigenetics, DNA methylation, histone modifications, psychoses, schizophrenia, bipolar disorder and environmental risks associated with psychotic disorders as observed in human and experimental animal studies, complemented by review articles and cross-references.
resultsDespite several promising findings of differential epigenetic profiles in individuals with psychotic disorders in the studies published to date, the knowledge of the role of epigenetic processes in psychotic disorder remains very limited, and should be interpreted cautiously given various challenges in this rapidly evolving field of research.
conclusionsIntegration of epigenetic findings into biopsychosocial models of the etiology of psychotic disorders eventually may yield important insights into the biological underpinnings of the onset and course of psychotic disorders.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.